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16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus

  • Shaye Kivity1, 2Email author,
  • Aviva Katzav1, 3,
  • Maria Teresa Arango1, 4, 5,
  • Moran Landau-Rabi1,
  • Yaron Zafrir1,
  • Nancy Agmon-Levin1,
  • Miri Blank1,
  • Juan-Manuel Anaya4,
  • Edna Mozes6,
  • Joab Chapman1, 3 and
  • Yehuda Shoenfeld1, 7
Contributed equally
BMC Medicine201311:90

DOI: 10.1186/1741-7015-11-90

Received: 28 September 2012

Accepted: 13 December 2012

Published: 4 April 2013

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
28 Sep 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
Resubmission - Version 4
Submitted Manuscript version 4
Resubmission - Version 5
Submitted Manuscript version 5
22 Oct 2012 Reviewed Reviewer Report - Elena Ortona
22 Oct 2012 Reviewed Reviewer Report - Takahisa Gono
13 Nov 2012 Author responded Author comments - Shaye Kivity
Resubmission - Version 6
13 Nov 2012 Submitted Manuscript version 6
27 Nov 2012 Reviewed Reviewer Report - Takahisa Gono
9 Dec 2012 Author responded Author comments - Shaye Kivity
Resubmission - Version 7
9 Dec 2012 Submitted Manuscript version 7
17 Dec 2012 Author responded Author comments - Shaye Kivity
Resubmission - Version 8
17 Dec 2012 Submitted Manuscript version 8
Publishing
13 Dec 2012 Editorially accepted
4 Apr 2013 Article published 10.1186/1741-7015-11-90

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article.. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
The Zabludovicz Center for Autoimmune Diseases, Sheba Medical Center
(2)
Rheumatic Disease Unit, Sheba Medical Center
(3)
Department of Neurology, Sagol Neuroscience Center, Sheba Medical Center
(4)
Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario
(5)
Doctoral Program in Biomedical Sciences, Universidad del Rosario
(6)
Department of Immunology, The Weizmann Institute of Science
(7)
Incumbent of the Laura Schwarz-Kip Chair for Research of Autoimmune Diseases, Sackler Faculty of Medicine, Tel-Aviv University

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