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Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis

  • Georg M Fröhlich1,
  • Alexandra J Lansky2,
  • John Webb3,
  • Marco Roffi4,
  • Stefan Toggweiler5,
  • Markus Reinthaler1,
  • Duolao Wang6,
  • Nevil Hutchinson7,
  • Olaf Wendler8,
  • David Hildick-Smith9 and
  • Pascal Meier1, 2Email author
BMC Medicine201412:41

DOI: 10.1186/1741-7015-12-41

Received: 20 September 2013

Accepted: 13 February 2014

Published: 10 March 2014

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
20 Sep 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
8 Oct 2013 Reviewed Reviewer Report - Brahmajee Nallamothu
10 Oct 2013 Reviewed Reviewer Report - Jan Piek
20 Jan 2014 Author responded Author comments - Pascal Meier
Resubmission - Version 3
20 Jan 2014 Submitted Manuscript version 3
13 Feb 2014 Editorially accepted
10 Mar 2014 Article published 10.1186/1741-7015-12-41

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

The Heart Hospital, University College London Hospitals
Division of Cardiology, Yale Medical School
Department of Cardiology, St. Paul’s Hospital, University of British Columbia
Department of Cardiology, University Hospital Geneva HUGE
Department of Cardiology, Kantonsspital Luzern
Department of Medical Statistics, London School of Hygiene and Tropical Medicine London
Division of Anesthesiology, Brighton and Sussex University Hospital
Department of Cardiothoracic Surgery, King’s College Hospital
Division of Cardiology, Brighton and Sussex University Hospital