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The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

  • Karim Malki1Email author,
  • Robert Keers1Email author,
  • Maria Grazia Tosto1, 2,
  • Anbarasu Lourdusamy3,
  • Lucia Carboni4,
  • Enrico Domenici5, 6,
  • Rudolf Uher1, 7,
  • Peter McGuffin1 and
  • Leonard C Schalkwyk1
Contributed equally
BMC Medicine201412:73

DOI: 10.1186/1741-7015-12-73

Received: 13 November 2013

Accepted: 10 April 2014

Published: 7 May 2014

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
13 Nov 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
15 Dec 2013 Reviewed Reviewer Report - Artur Swiergiel
7 Jan 2014 Reviewed Reviewer Report - Catharina Lavebratt
9 Feb 2014 Author responded Author comments - Karim Malki
Resubmission - Version 3
9 Feb 2014 Submitted Manuscript version 3
9 Feb 2014 Author responded Author comments - Karim Malki
Resubmission - Version 4
9 Feb 2014 Submitted Manuscript version 4
Resubmission - Version 5
Submitted Manuscript version 5
3 Mar 2014 Reviewed Reviewer Report - Artur Swiergiel
6 Mar 2014 Reviewed Reviewer Report - Catharina Lavebratt
26 Mar 2014 Reviewed Reviewer Report - Alessio Squassina
4 Apr 2014 Author responded Author comments - Karim Malki
Resubmission - Version 6
4 Apr 2014 Submitted Manuscript version 6
Publishing
10 Apr 2014 Editorially accepted
7 May 2014 Article published 10.1186/1741-7015-12-73

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
King’s College London, MRC Social, Genetic and Developmental Psychiatry Centre, at Institute of Psychiatry, SGDP Research Centre (PO80)
(2)
Department of Psychology, University of York
(3)
Queen’s Medical Centre, University of Nottingham
(4)
Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna
(5)
Center of Excellence for Drug Discovery in Neuroscience, GlaxoSmithKline Medicines Research Centre
(6)
Pharma Research and Early Development
(7)
Department of Psychiatry, Dalhousie University

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