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The Gly2019Ser mutation in LRRK2is not fully penetrant in familial Parkinson's disease: the GenePD study

  • Jeanne C Latourelle1Email author,
  • Mei Sun2,
  • Mark F Lew3,
  • Oksana Suchowersky4,
  • Christine Klein5,
  • Lawrence I Golbe6,
  • Margery H Mark6,
  • John H Growdon7,
  • G Frederick Wooten8,
  • Ray L Watts9,
  • Mark Guttman10,
  • Brad A Racette11,
  • Joel S Perlmutter11,
  • Anwar Ahmed12,
  • Holly A Shill13,
  • Carlos Singer14,
  • Stefano Goldwurm15,
  • Gianni Pezzoli15,
  • Michela Zini15,
  • Marie H Saint-Hilaire1,
  • Audrey E Hendricks1, 16,
  • Sally Williamson1,
  • Michael W Nagle1,
  • Jemma B Wilk1,
  • Tiffany Massood1,
  • Karen W Huskey1,
  • Jason M Laramie1,
  • Anita L DeStefano1, 16,
  • Kenneth B Baker17,
  • Ilia Itin17,
  • Irene Litvan18,
  • Garth Nicholson19,
  • Alastair Corbett19,
  • Martha Nance20,
  • Edward Drasby21,
  • Stuart Isaacson22,
  • David J Burn23,
  • Patrick F Chinnery24,
  • Peter P Pramstaller25,
  • Jomana Al-hinti26,
  • Anette T Moller27,
  • Karen Ostergaard27,
  • Scott J Sherman28,
  • Richard Roxburgh29,
  • Barry Snow29,
  • John T Slevin30,
  • Franca Cambi30,
  • James F Gusella2 and
  • Richard H Myers1
BMC Medicine20086:32

DOI: 10.1186/1741-7015-6-32

Received: 08 September 2008

Accepted: 05 November 2008

Published: 05 November 2008

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
8 Sep 2008 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
Publishing
5 Nov 2008 Editorially accepted
5 Nov 2008 Article published 10.1186/1741-7015-6-32

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Neurology, Boston University School of Medicine, Boston University
(2)
Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School
(3)
Department of Neurology, University of Southern California
(4)
Departments of Clinical Neurosciences and Medical Genetics, University of Calgary
(5)
Department of Neurology, Medical University of Lübeck
(6)
Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School
(7)
Department of Neurology, Massachusetts General Hospital, Harvard Medical School
(8)
Department of Neurology, University of Virginia Health System
(9)
Department of Neurology, University of Alabama at Birmingham
(10)
Department of Medicine, University of Toronto
(11)
Department of Neurology, Washington University School of Medicine
(12)
Barrow Neurological Institute
(13)
Sun Health Research Institute
(14)
Department of Neurology, University of Miami
(15)
Parkinson Institute, Istituti Clinici di Perfezionamento
(16)
Department of Biostatistics, Boston University School of Medicine, Boston University
(17)
Departments of Neurology and Neuroscience, Cleveland Clinic Foundation
(18)
Department of Neurology, University of Louisville School of Medicine
(19)
Neurology Department, University of Sydney ANZAC Research Institute, Concord Hospital
(20)
Struthers Parkinson's Center, Park Nicollet Clinic
(21)
Port City Neurology
(22)
Parkinson's Disease and Movement Disorder Center of Boca Raton
(23)
Institute for Ageing and Health, Newcastle University
(24)
Regional Neurosciences Centre, Newcastle University
(25)
Department of Neurology, General Regional Hospital Bolzano
(26)
Department of Neurology, University of Arkansas for Medical Sciences
(27)
Department of Neurology, Aarhus University Hospital
(28)
Department of Neurology, University of Arizona
(29)
Department of Neurology, Auckland City Hospital
(30)
Department of Neurology, University of Kentucky College of Medicine

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