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This article has Open Peer Review reports available.

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α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostanaLinn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

  • Masa-Aki Shibata1, 2Email author,
  • Munekazu Iinuma3,
  • Junji Morimoto4,
  • Hitomi Kurose2,
  • Kanako Akamatsu5,
  • Yasushi Okuno5,
  • Yukihiro Akao6 and
  • Yoshinori Otsuki2
BMC Medicine20119:69

DOI: 10.1186/1741-7015-9-69

Received: 20 January 2011

Accepted: 3 June 2011

Published: 3 June 2011

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
20 Jan 2011 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
27 Jan 2011 Reviewed Reviewer Report - Airo TSUBURA
12 Feb 2011 Reviewed Reviewer Report - Manabu Kawada
14 Feb 2011 Reviewed Reviewer Report - Yian Wang
11 Mar 2011 Author responded Author comments - Masa-Aki Shibata
Resubmission - Version 3
11 Mar 2011 Submitted Manuscript version 3
22 Mar 2011 Reviewed Reviewer Report - Manabu Kawada
28 Mar 2011 Reviewed Reviewer Report - Yian Wang
19 Apr 2011 Author responded Author comments - Masa-Aki Shibata
Resubmission - Version 4
19 Apr 2011 Submitted Manuscript version 4
8 May 2011 Author responded Author comments - Masa-Aki Shibata
Resubmission - Version 5
8 May 2011 Submitted Manuscript version 5
Publishing
3 Jun 2011 Editorially accepted
3 Jun 2011 Article published 10.1186/1741-7015-9-69

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Laboratory of Anatomy and Histopathology, Faculty of Health Science, Osaka Health Science University
(2)
Department of Anatomy and Cell Biology, Division of Life Sciences, Osaka Medical College
(3)
Laboratory of Pharmacognosy, Gifu Pharmaceutical University
(4)
Laboratory Animal Center, Osaka Medical College
(5)
Department of Systems Bioscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University
(6)
United Graduate School of Drug Discovery and Medical Information Science, Gifu University

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