Figure 1
From: Clinical application of stem cell therapy in Parkinson's disease
Human fetal ventral mesencephalic tissue grafts provide long-lasting major relief of motor symptoms (reductions in UPDRS motor scores) and restore dopamine innervation (increases in 18F-DOPA PET uptake) in the grafted striatum in Patients 7 (A) and 15 (B) from the Lund series (modified figure from [4]). Patient 7 and Patient 15 stopped receiving any form of dopaminergic medication four and five years following operation, respectively. PET = Positron emission tomography; UPDRS = Unified Parkinson's Disease Rating Scale.