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Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?

  • Sabrina Ehnert1Email author,
  • Jian Zhao2,
  • Stefan Pscherer3,
  • Thomas Freude1,
  • Steven Dooley4,
  • Andreas Kolk5,
  • Ulrich Stöckle1,
  • Andreas Klaus Nussler1, 2 and
  • Robert Hube6
Contributed equally
BMC Medicine201210:101

https://doi.org/10.1186/1741-7015-10-101

Received: 7 March 2012

Accepted: 7 September 2012

Published: 7 September 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
7 Mar 2012 Submitted Original manuscript
Author responded Author comments
Reviewed Reviewer Report
Reviewed Reviewer Report
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
Author responded Author comments
Reviewed Reviewer Report
Reviewed Reviewer Report
Resubmission - Version 4
Submitted Manuscript version 4
Author responded Author comments
Resubmission - Version 5
Submitted Manuscript version 5
Publishing
7 Sep 2012 Editorially accepted
7 Sep 2012 Article published 10.1186/1741-7015-10-101

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
BG Trauma Center, Eberhard Karls Universität Tübingen
(2)
Department of Traumatology, MRI, Technische Universität München
(3)
Department Nephrology, Klinikum Traunstein, Kliniken Südostbayern AG
(4)
Department of Medicine II, University Hospital Mannheim, Ruprecht-Karls-Universität Heidelberg
(5)
Department of Oro- and Maxillofacial Surgery, MRI, Technische Universität München
(6)
Department of Orthopaedic Surgery, OCM-Clinic Munich

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