From: Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study
Parameter | |
---|---|
Patients, n | 120 |
Male, n (%) | 77 (64.2) |
Age, mean ± SD (years) | 56.1 ± 11.8 |
Weight, mean ± SD (kg) | 77.8 ± 17.0 |
Hematology | |
Hb, mean ± SD (g/dl) | 11.1 ± 2.8 |
Leukocytes, mean ± SD (10³) | 6.8 ± 4.1 |
Thrombocytes, mean ± SD (/nl) | 134.5 ± 167.3 |
Biochemistry | |
AST, mean ± SD (U/l) | 74.9 ± 116.5 |
ALT, mean ± SD (U/l) | 55.1 ± 150.5 |
GGT, mean ± SD (U/l) | 186.6 ± 209.6 |
AP, mean ± SD (U/l) | 148.2 ± 82.0 |
Total bilirubin, mean ± SD (mg/dl) | 3.6 ± 5.6 |
INR, mean ± SD | 2.3 ± 8.2 |
CRP, mean ± SD (ng/ml) | 2.3 ± 3.1 |
Albumin, mean ± SD (g/l) | 3.2 ± 0.6 |
Creatinine, mean ± SD (mg/dl) | 1.3 ± 0.9 |
Prognosis score | |
MELD, mean (range) | 16.3 (6.2 to 35.6) |
Liver-related complications | |
Ascites, n (%) | 68 (56.7) |
Hepatorenal syndrome, n (%) | 26 (21.7) |
Spontaneous bacterial peritonitis, n (%) | 13 (10.8) |
Hepatic encephalopathy, n (%) | 25 (20.8) |
Variceal bleeding, n (%) | 10 (8.3) |
Etiology of liver disease | |
Chronic hepatitis B, n (%) | 10 (8.3) |
Chronic hepatitis C, n (%) | 34 (28.3) |
Alcohol, n (%) | 54 (45.0) |
PSC, n (%) | 4 (3.3) |
PBC, n (%) | 2 (1.7) |
Autoimmune, n (%) | 3 (2.5) |
Hemochromatosis n (%) | 2 (1.7) |
NASH, n (%) | 2 (1.7) |
Toxic, n (%) | 2 (1.7) |
Alpha1 antitrypsin deficiency | 1 (0.8) |
Cryptogenic | 6 (5.0) |