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Table 4 Altered genes in microarray according to prostatic disease status (overall, OB/OW or lean group)

From: Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue

Probe set Gene Name Gene Description Fold Change P
Extra Prostatic Cancer versus Benign Prostatic Hyperplasia   
All subjects     
7952313 MIRLET7A2 microRNA let-7a-2 2.00 4.26E-06
7957540 MRPL42 mitochondrial ribosomal protein L42 1.63 5.49E-06
7980891 TC2N tandem C2 domains; nuclear 2.25 8.26E-06
7915468 CCDC23 coiled-coil domain containing 23 1.70 1.93E-05
8002020 TPPP3 tubulin polymerization-promoting protein family member 3 1.66 8.62E-05
7980861 CATSPERB cation channel; sperm-associated; beta 1.84 1.48E-04
7964927 TSPAN8 tetraspanin 8 1.91 2.31E-04
8168463 FGF16 fibroblast growth factor 16 1.67 2.93E-04
Lean subjects    
7952313 MIRLET7A2 microRNA let-7a-2 2.12 9.04E-05
8024485 GADD45B growth arrest and DNA-damage-inducible; beta -1.56 9.47E-04
7957540 MRPL42 mitochondrial ribosomal protein L42 1.60 9.86E-04
OB/OW subjects    
7980861 CATSPERB cation channel; sperm-associated; beta 2.50 1.91E-06
7980891 TC2N tandem C2 domains; nuclear 2.98 4.31E-06
7908488 CFHR1 complement factor H-related 1 1.88 3.16E-05
8078529 STAC SH3 and cysteine rich domain 1.50 5.79E-05
7902400 SNORD45B small nucleolar RNA; C/D box 45B -5.18 1.9E-04
7908459 CFH complement factor H 1.70 3.0E-04
7952313 MIRLET7A2 microRNA let-7a-2 1.88 4.0E-04
7957540 MRPL42 mitochondrial ribosomal protein L42 1.65 4.0E-04
7958019 DRAM1 DNA-damage regulated autophagy modulator 1 1.55 5.3E-04
7969640 CLDN10 claudin 10 1.59 6.3E-04
8076586 SCUBE1 signal peptide; CUB domain; EGF-like 1 -1.73 7.2E-04
8027862 FFAR2 free fatty acid receptor 2 -1.58 9.2E-04
Organ Confined Prostate Cancer versus Benign Prostatic Hyperplasia   
All subjects     
7919349 RNU1-1 RNA; U1 small nuclear 1 -2.18 1.50E-07
7919576 RNU1-1 RNA; U1 small nuclear 1 -1.96 2.47E-07
7952313 MIRLET7A2 microRNA let-7a-2 1.79 6.21E-05
7980891 TC2N tandem C2 domains; nuclear 1.98 6.26E-05
7978568 RNU1-1 RNA; U1 small nuclear 1 -1.65 9.43E-05
7981964 SNORD116-8 small nucleolar RNA; C/D box 116-8 -1.91 1.07E-04
8004184 XAF1 XIAP associated factor 1 -1.64 8.67E-04
Lean subjects    
8001067 HERC2P4 hect domain and RLD 2 pseudogene 4 -1.77 1.22E-06
7997239 PDXDC2 pyridoxal-dependent decarboxylase domain containing 2 -2.12 2.69E-06
8000692 BOLA2 bolA homolog 2 (E, coli) -1.52 3.41E-06
8000651 SMG1 SMG1 homolog; phosphatidylinositol 3-kinase-related kinase (C. elegans) -1.61 3.76E-06
8019655 TBC1D3B TBC1 domain family; member 3B -1.56 1.26E-05
7919349 RNU1-1 RNA; U1 small nuclear 1 -2.30 2.27E-05
7927513 FAM21C family with sequence similarity 21; member C -1.66 2.31E-05
7993359 NPIP nuclear pore complex interacting protein -1.53 4.30E-05
8014633 TBC1D3 TBC1 domain family; member 3 -1.55 5.53E-05
8014437 TBC1D3G TBC1 domain family; member 3G -1.51 6.27E-05
7994026 NPIPL3 nuclear pore complex interacting protein-like 3 -1.69 9.02E-05
OB/OW subjects    
7969640 CLDN10 claudin 10 2.01 7.04E-06
7980891 TC2N tandem C2 domains; nuclear 2.31 1.10E-04
7952313 MIRLET7A2 microRNA let-7a-2 2.06 1.74E-04
8021101 HAUS1 HAUS augmin-like complex; subunit 1 1.61 3.10E-04
8165698 MIR1977 microRNA 1977 -3.03 3.46E-04
8060854 PLCB1 phospholipase C; beta 1 (phosphoinositide-specific) 1.53 5.95E-04
Extra Prostatic Cancer versus Organ Confined Prostate Cancer   
All subjects     
7919349 RNU1-1 RNA; U1 small nuclear 1 1.71 1.86E-05
7981964 SNORD116-8 small nucleolar RNA; C/D box 116-8 1.88 1.85E-04
7940287 MS4A1 membrane-spanning 4-domains; subfamily A; member 1 -2.15 2.74E-04
Lean subjects    
8001067 HERC2P4 hect domain and RLD 2 pseudogene 4 2.06 5.14E-08
8000692 BOLA2 bolA homolog 2 (E, coli) 1.52 3.37E-06
7997239 PDXDC2 pyridoxal-dependent decarboxylase domain containing 2 2.00 6.36E-06
8000651 SMG1 SMG1 homolog; phosphatidylinositol 3-kinase-related kinase (C. elegans) 1.57 6.75E-06
7927513 FAM21C family with sequence similarity 21; member C 1.74 8.44E-06
7993359 NPIP nuclear pore complex interacting protein 1.51 5.38E-05
7994026 NPIPL3 nuclear pore complex interacting protein-like 3 1.73 5.61E-05
8119595 RPL7L1 ribosomal protein L7-like 1 1.63 5.71E-05
7990943 GOLGA6L10 golgin A6 family-like 10 1.55 6.08E-05
7919349 RNU1-1 RNA; U1 small nuclear 1 1.93 2.25E-04
OB/OW subjects    
7980861 CATSPERB cation channel; sperm-associated; beta 1.78 2.92E-04
7982006 SNORD116-29 small nucleolar RNA; C/D box 116-29 1.77 5.84E-04
  1. The bold ones with adjusted P <0.2