|
Ferritin as indicators of body iron stores (n = 5)
| | |
|
Jiang et al, 2004, USA [10]
|
Women
|
Highest (≥107.2 ng/ml) versus lowest (<21.1 ng/ml) quintile
|
Model 1a
|
2.68 (1.75 to 4.11)
|
Age, ethnicity, fasting status, BMI, FH, PA, smoking, alcohol consumption, menopausal status, glycemic load, intake of total energy, cereal fiber, magnesium, and trans fat, and ratio of polyunsaturated fat to saturated fat
|
| | | |
Model 2b
|
2.61 (1.68 to 4.07)
|
Additional adjustment for CRP
|
|
Forouhi et al, 2007, UKc [11]
|
Men
|
Highest (≥135.7 ng/ml) versus lowest (<34.4 ng/ml) quintile
|
Model 1a
|
1.97 (1.12 to 3.45)
|
Age, sex, BMI, FH, PA, smoking, dietary factors (TEI, alcohol consumption, intake of dietary iron, magnesium, and red meat and processed meat, plasma vitamin C)
|
| | | |
Model 2b
|
1.78 (0.99 to 3.19)
|
Additional adjustment for CRP, fibrinogen, and IL-6
|
| | | |
Model 3
|
1.13 (0.58, 2.19)
|
Additional adjustment for ALT, GGT, and adiponectin
|
| |
Women
|
Highest (≥71.7 ng/ml) versus lowest (<17.8 ng/ml) quintile
|
Model 1a
|
2.55 (1.22 to 5.34)
|
Age, sex, BMI, FH, PA, smoking, dietary factors (TEI, alcohol consumption, intake of dietary iron, magnesium, red meat and processed meat and plasma vitamin C)
|
| | | |
Model 2b
|
2.11 (0.98 to 4.56)
|
Additional adjustment for CRP, fibrinogen, and IL-6
|
| | | |
Model 3
|
1.08 (0.44, 2.62)
|
Additional adjustment for ALT, GGT, and adiponectin
|
|
Jehn et al, 2007, USA [15]
|
Both
|
Highest (≥235.4 ng/ml; median, 354.5 ng/ml) versus lowest (<40.0 ng/ml; median, 20.0 ng/ml)quintile
|
Model 1a
|
1.51 (0.98 to 2.31)
|
Age, study center, ethnicity, smoking, alcohol consumption, and BMI
|
| | | |
Model 2
|
0.81 (0.49 to 1.34)
|
Additional adjustment for metabolic syndrome components (HDL-C, WC, hypertension, FPG, and TG)
|
| | | |
Model 3b
|
0.79 (0.48 to 1.32)
|
Additional adjustment for FPI and inflammation score
|
|
Le et al, 2009, USA [16]
|
Men
|
Highest (>188 ng/ml) versus lowest (<80 ng/ml) quartile
|
Model 1a
|
1.79 (1.13 to 2.82)
|
Age, ethnicity, and BMI
|
| |
Women
|
Highest (premenopausal, >60 ng/ml, postmenopausal, >90 ng/ml) versus lowest (premenopausal,<21 ng/ml, postmenopausal,<37 ng/ml) quartile
|
Model 1a
|
0.87 (0.37 to 2.03)
|
Age, ethnicity, and BMI
|
|
Rajpathak et al, 2009, USA [17]
|
Both
|
Highest (median, 203.7 ng/ml) versus lowest (median, 20.1 ng/ ml) quartile
|
Model 1a
|
1.02 (0.60 to 1.74)
|
Age, sex, ethnicity, and BMI
|
| | | |
Model 2
|
1.65 (0.90 to 3.02)
|
Additional adjustment for FH, PA, HbA1c, and sTfR
|
| | | |
Model 3b
|
1.53 (0.83 to 2.82)
|
Additional adjustment for CRP
|
| | | |
Model 4
|
1.61 (0.85 to 3.02)
|
Additional adjustment for HOMA-IR
|
|
Ratio of sTfR to ferritin as indicators of body iron stores (n = 2)
| | |
|
Salonen et al, 1998, Finland [9]
|
Men
|
Highest (< 9.4) versus quartile (no data available)
|
Model 1
|
2.40 (1.03 to 5.50)
|
Age, time of examination, place of residence, cigarette smoking, exercise, maximal oxygen uptake, socioeconomic status, height, weight, hip and waist circumferences, glucose, insulin, vitamin E, and serum SFA to (PUFA + MUFA) ratio
|
|
Jiang et al, 2004, USA [10]
|
Women
|
Highest (<26.7) versus lowest (≥149.4) quintile
|
Model 1
|
2.44 (1.61 to 3.71)
|
Age, ethnicity, fasting status, BMI, FH, PA, smoking, alcohol consumption, menopausal status, glycemic load, intake of total energy, cereal fiber, magnesium, and trans fat, ratio of polyunsaturated fat to saturated fat
|
| | | |
Model 2
|
2.40 (1.55 to 3.71)
|
Additional adjustment for CRP
|
|
sTfR as indicators of body iron stores (n = 1)
| | |
|
Rajpathak et al, 2009, USA [17]
|
Both
|
Highest (median, 4.4 mg/l) versus lowest (median, 2.3 mg/l) quartile
|
Model 1
|
1.55 (0.93 to 2.57)
|
Age, sex, ethnicity, and BMI
|
| | | |
Model 2
|
2.26 (1.27 to 4.01)
|
Additional adjustment for FH, PA, HbA1c, and sTfR
|
| | | |
Model 3
|
2.39 (1.34 to 4.28)
|
Additional adjustment for CRP
|
| | | |
Model 4
|
2.23 (1.22 to 4.06)
|
Additional adjustment for HOMA-IR
|
