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Table 3 Prevalence and incidence density of chronic comorbidity: overall, before, at time of, and after diabetes diagnosis (DD)1,2

From: Prevalence and incidence density rates of chronic comorbidity in type 2 diabetes patients: an exploratory cohort study

Time Extent of chronic comorbidity
   ≥ 1 chronic comorbid disease ≥ 3 chronic comorbid diseases ≥ 3 clusters3
   All Discordant4 only All Discordant4 only All Discordant4 only
Before diabetes ID, year before DD5 259.3 (169.4 to 349.1) 106.2 (61.8 to 150.6) 101.9 (69.5 to 134.3) 42.9 (25.0 to 60.8) 78.8 (52.7 to 104.9) 45.4 (27.6 to 63.3)
  Prevalence6 at DD, % (95% CI) 84.6 (81.8 to 87.1) 70.6 (67.2 to 73.9) 48.6 (44.9 to 52.3) 27.2 (24.0 to 30.5) 38.0 (34.5 to 41.6) 22.0 (19.1 to 25.1)
After diabetes ID, first year after DD5 263.7 (160.3 to 367.0) 88.3 (46.3 to 130.2) 80.9 (50.4 to 111.4) 38.9 (21.4 to 56.4) 48.3 (27.1 to 69.5) 30.4 (15.5 to 45.4)
  ID, first 5 years after DD5 160.2 (116.2 to 204.2) 83.9 (62.3 to 105.5) 91.2 (74.1 to 108.3) 45.1 (35.3 to 54.8) 59.5 (47.3 to 71.6) 36.3 (27.9 to 44.6)
  ID, first 10 years after DD5 142.5 (107.0 to 177.9) 84.5 (66.0 to 103.0) 84.8 (70.6 to 99.1) 47.7 (39.2 to 56.1) 62.5 (51.9 to 73.1) 37.6 (30.4 to 44.7)
  1. Abbreviations: ID, incidence density.
  2. 1This table displays data on the presence and occurrence of one (the first) and of three (the third) chronic comorbid disease(s), and on the presence and occurrence of three (the third) cluster(s) of chronic comorbid disease(s) respectively.
  3. 2Confidence intervals (CIs) for proportions were calculated with the Mid-P exact test. CIs for person time were calculated as a normal approximation to the Poisson interval.
  4. 3Clusters: comorbid diseases were classified into clusters, following The International Classification of Primary Care (ICPC)-1 chapters.
  5. 4Discordant: without shared pathogenesis, risk factors or management.
  6. 5Incidence density displays the number of new occurrences of the specified number of chronic comorbid diseases or clusters of comorbidity, divided by the number of person-years at risk within the specified period. Expressed as number of new cases per 1,000 patient-years at risk (95% CI).
  7. 6Prevalence at diabetes date displays the proportion of patients in whom (at least) the specified number of chronic comorbid diseases, or clusters of comorbidity, had been diagnosed at this date.