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Figure 4 | BMC Medicine

Figure 4

From: Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy

Figure 4

Effect of catalase (CAT) overexpression on LeTx-induced cardiomyocyte mitochondrial damage. A: Representative fluorescent images of JC-1 in control and LeTx exposure conditions. CCCP (10 μM) was used as a positive control; B: Summarized JC-1 ratio representing mitochondrial membrane potential in response to LeTx and CCCP exposure; and C: Cardiomyocyte mitochondrial membrane potential over time. Mean ± SEM, n = 6 isolations per group, *P <0.05 vs. WT group, #P <0.05 vs. WT-LeTx group.

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