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Table 3 Predictors of case fatality among children with severe pneumonia, Mulago Hospital, Ugandaa

From: Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial

Variable

RR (Unadjusted) 95% CI

RR (adjusted)b 95% CI

RR (adjusted)c 95% CI

Zinc adjunct therapy

0.3 (0.1,0.8)

0.3 (0.1, 0.97)

0.2 (0.0, 1.1)

WHZ

   

   <-2SD

0.29 (0.1, 0.6)

0.3 (0.1, 0.8)

0.3 (0.1, 0.7)

Oxygen saturation

   

   < 92%

2.4 (1.1, 5.1)

1.6 (0.6, 3.9)

1.4 (0.6, 3.3)

HIV status

   

   Positive

2.7 (1.1, 6.6)

2.6 (1.0, 6.7)

4.3 (1.4, 12.7)

Age

   

   6 to 12

1.0 (0.5, 2.0)

  

   13 to 24

0.1 (0.0, 1.1)

  

Caretaker relationship to child

   

   Other

0.8 (0.2, 3.2)

  

Blood culture positive

1.8 (0.6, 6.0)

  

Zinc adjunct therapy* HIV statusd

  

5.5 (0.5, 58.3)

  1. a CI, confidence interval
  2. b Only variables with a P-value less than 0.25 in the unadjusted analysis were included in this model.
  3. c Model includes variables with a P-value less than 0.25 and the interaction term for HIV status and Zinc
  4. d Cross-product (interaction) term for HIV status and zinc