Comparisons | No. of new lesions | No. of subjects | t Test |
Pvalue |
---|
t1 to t2 | -0.08 (0.82) | 12 | -0.35 | 0.732 |
t2 to t3 | -0.36 (0.64) | 11 | -1.90 | 0.087 |
t3 to t4 | 0.17 (0.52) | 6 | 0.79 | 0.465 |
|
Volume change of lesions
| | | |
t1 to t2 | 54.9 (247.4) | 12 | 0.77 | 0.458 |
t2 to t3 | 38.3 (116.9) | 11 | 1.09 | 0.302 |
t3 to t4 | -100.42 (237.7) | 6 | -1.03 | 0.348 |
- t1 = timepoint 1, start of the race; t2 = timepoint 2, after an average distance of 2,326 km; t3 = timepoint 3, after an average distance of 4,005 km from t1; t4 = timepoint 4, follow-up measurements around 8 months after finishing the race. No. of new lesions = across participants averaged number of new lesions (SD) observed between two consecutive timepoints. No. of subjects = number of subjects with two consecutive FLAIR measurements to enter a paired t test. Volume change of lesions = for calculation of lesion volumes see Methods section, shown is the difference between averaged sums of lesion volumes obtained at two consecutive timepoints, units are mm3.