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Table 3 Lesion statistics from serial fluid-attenuated inversion recovery (FLAIR) imaging

From: Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project

Comparisons No. of new lesions No. of subjects t Test Pvalue
t1 to t2 -0.08 (0.82) 12 -0.35 0.732
t2 to t3 -0.36 (0.64) 11 -1.90 0.087
t3 to t4 0.17 (0.52) 6 0.79 0.465
  Volume change of lesions    
t1 to t2 54.9 (247.4) 12 0.77 0.458
t2 to t3 38.3 (116.9) 11 1.09 0.302
t3 to t4 -100.42 (237.7) 6 -1.03 0.348
  1. t1 = timepoint 1, start of the race; t2 = timepoint 2, after an average distance of 2,326 km; t3 = timepoint 3, after an average distance of 4,005 km from t1; t4 = timepoint 4, follow-up measurements around 8 months after finishing the race. No. of new lesions = across participants averaged number of new lesions (SD) observed between two consecutive timepoints. No. of subjects = number of subjects with two consecutive FLAIR measurements to enter a paired t test. Volume change of lesions = for calculation of lesion volumes see Methods section, shown is the difference between averaged sums of lesion volumes obtained at two consecutive timepoints, units are mm3.