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Table 4 Evolution of weight and gray matter (GM) brain volume during the TransEurope-FootRace 2009 (TEFR09)

From: Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project

Parameter Weight in kg, 7s group GM volume in ml, 7s group Weight in kg, 10s group GM volume in ml, 10s group
Timepoint 1, start 75.1 (6.8) 670.0 (38.1) 73.6 (6.6) 671.7 (46.1)
Timepoint 2, 2,400 km 71.2 (6.3)* 642.9 (38.8)** 70.0 (5.8)*** 645.5 (38.6)****
Timepoint 3, 4,005 km 70.5 (6.4)* 630.5 (42.6)** 69.2 (5.9)*** 630.7 (49.4)****
Timepoint 4, follow-up 76.5 (6.2)* 671.1 (19.5)** NA NA
Difference, timepoint 1-2 3.9 (P = 0.0002) 27.1 (P = 0.006) 3.6 (P = 0.0002) 26.2 (P = 0.0013)
Difference, timepoint 1-3 4.6 (P = 0.0002) 39.5 (P = 0.008) 4.4 (P = 0.0002) 40.6 (P = 0.0002)
Difference, timepoint 2-3 0.7 (0.419) 12.4 (P = 0.172) 0.8 (P = 0.159) 14.4 (P = 0.042)
Difference, timepoint 4-3 6.0 (P = 0.0002) 40.6 (P = 0.001) NA NA
Difference, timepoint 4-1 1.4 (P = 0.092) 1.1 (P = 0.898) NA NA
  1. Values are mean (SD).
  2. *P <0.0001 analysis of variance for effect of time with F(3,18) = 28.42; **P <0.001 analysis of variance for effect of time with F(3,18) = 10.70; ***P <0.0001 analysis of variance for effect of time with F(2,18) = 34.19; ****P <0.0001 analysis of variance for effect of time with F(2,18) = 18.76.
  3. 10s group = ten-subject group; 7s group = seven-subject group; NA = not applicable.