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Table 3 Main findings (primary outcomes).

From: Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis

  All-cause mortality Myocardial infarction Stroke
Diuretics vs.BB 0.90 (0.80 to 1.01) 0.82 (0.68 to 0.98) 0.83 (0.68 to 1.07)
  O OO OO
Diuretics vs. ACE 1.00 (0.93 to 1.08) 1.00 (0.88 to 1.15) 0.94 (0.81 to 1.10)
  O O O
Diuretics vs. CCB 1.03 (0.96 to 1.10) 0.96 (0.84 to 1.07) 1.12 (0.97 to 1.29)
  O O OO
Diuretics vs.alpha-blockers 0.98 (0.87 to 1.12) 0.99 (0.80 to 1.23) 0.85 (0.66 to 1.12)
  O O OO
Diuretics vs.ARB 1.02 (0.92 to 1.14) 0.83 (0.69 to 1.03) 1.02 (0.82 to 1.28)
  OO OOO OOO
BB vs. ACE 1.12 (0.98 to 1.27) 1.22 (1.00 to 1.52) 1.13 (0.86 to 1.42)
  OOO OO OOO
BB vs. CCB 1.14 (1.01 to 1.28) 1.17 (0.97 to 1.42) 1.34 (1.05 to 1.64)
  OO OOO OO
BB vs. alpha-blockers 1.09 (0.93 to 1.30) 1.20 (0.92 to 1.61) 1.02 (0.71 to 1.42)
  OOO OOO OOO
BB vs. ARB 1.14 (1.02 to 1.28) 1.02 (0.84 to 1.27) 1.23 (0.96 to 1.49)
  O O
ACE vs. CCB 1.02 (0.95 to 1.10) 0.96 (0.83 to 1.07) 1.19 (1.03 to 1.38)
  O O O
ACE vs. alpha-blockers 0.98 (0.85 to 1.14) 0.99 (0.77 to 1.27) 0.91 (0.67 to 1.24)
  OO OOO OOO
ACE vs. ARB 1.02 (0.91 to 1.14) 0.84 (0.68 to 1.04) 1.08 (0.86 to 1.37)
  OO OOO OOO
CCB vs. alpha-blockers 0.96 (0.83 to 1.11) 1.03 (0.82 to 1.34) 0.77 (0.57 to 1.04)
  OO OOO OOO
CCB vs. ARB 1.00 (0.91 to 1.10) 0.87 (0.74 to 1.06) 0.91 (0.75 to 1.11)
  O O
Alpha-blockers vs. ARB 1.04 (0.88 to 1.23) 0.84 (0.63 to 1.14) 1.20 (0.85 to 1.69)
  OO OOO OOO
  1. ACE, Angiotensin Converting Enzyme Inhibitors; ARB, Angiotensin Receptor Blockers; BB, Beta-blockers; CCB, Calcium Channel Blockers; , High quality evidence; O, Moderate quality evidence; OO, Low quality evidence; OOO, Very low quality evidence