Figure 2
From: Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience
Neuron size and number in epilepsy relative to APOE genotype An apparent larger size of neurons (arrows) in patients with APOE ε3,3 (A) relative to those in patients with APOE ε4,4 (B) genotype was confirmed by computer assisted area measurements of individual neurons ( APOE ε3,3 = 356 ± 45 μm 2 vs APOE ε4,4 = 173 ± 27 μm 2 ; P < 0.001) (C and D). However, the numbers of neurons per image were similar for both genotypes (APOE ε3,3 = 21.5 ± 3.1 vs APOE ε4,4 = 24.0 ± 1.8; P = 0.18) (E and F).