Figure 1
From: Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery
Schematic outline of tissue-specific biomarker identification. Protein identification in six publicly available gene and protein databases, grouped by the type of data each database is based on, followed by filtering criteria and integration of proteomic datasets to identify and prioritize candidates is outlined. ESTs: expressed sequence tags; HPA: Human Protein Atlas; IHC: immunohistochemistry; TiGER: Tissue-specific and Gene Expression and Regulation.