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Table 3 List of colon tissue-specific proteins which have not been previously studied as serum cancer or benign disease biomarkers

From: Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery

Gene

Protein name

Proteome identified in:

  

CM proteome from colon cancer cell lines

Non-colon proteome

CEACAM7

Carcinoembryonic antigen-related cell adhesion molecule 7

 

√ CM proteome from Hep 3B [52]; pancreatic juice proteome [33]

CLCA1

Chloride channel accessory 1

 

√ Normal, Down Syndrome amniotic fluid [22, 23]

GPA33

Glycoprotein A33

√ LS174Ta, LS180a, Colo205 [52]

 

LEFTY1

Left-right determination factor 1

  

ZG16

Zymogen granule protein 16 homolog (rat)

 

√ CM proteome from Hep 3B [52]

  1. aCM proteome of colon cancer cell lines (GS Karagiannis et al., unpublished work). CM: conditioned media.