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Table 1 Biometric parameters of control or diabetic FVB and ALDH2 mice

From: Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function

Parameter FVB FVB-STZ ALDH2 ALDH2-STZ
Body weight (g) 30.3 ± 1.3 24.2 ± 0.7a 29.5 ± 1.1 26.1 ± 0.8a
Heart weight (mg) 165 ± 9 171 ± 8 163 ± 6 159 ± 5
Heart/body weight ratio (mg/g) 5.45 ± 0.19 7.23 ± 0.43a 5.66 ± 0.26 6.16 ± 0.18b
Liver weight (g) 1.54 ± 0.07 1.44 ± 0.07 1.52 ± 0.05 1.46 ± 0.06
Liver/body weight (mg/g) 51.2 ± 1.4 59.4 ± 2.3a 51.9 ± 1.9 54.9 ± 1.9
Kidney weight (g) 0.45 ± 0.03 0.39 ± 0.02 0.42 ± 0.02 0.40 ± 0.03
Kidney/body weight (mg/g) 14.8 ± 0.4 16.1 ± 0.8 14.4 ± 0.4 15.4 ± 0.8
Plasma insulin (ng/mL) 0.27 ± 0.03 0.05 ± 0.01a 0.28 ± 0.03 0.06 ± 0.02a
Fasting blood glucose (mM) 5.50 ± 0.26 19.7 ± 1.5a 5.43 ± 0.18 18.5 ± 1.7a
Postprandial blood glucose (mM) 9.94 ± 0.67 25.3 ± 1.5a 10.57 ± 0.54 26.5 ± 1.8a
Plasma free fatty acids (mM) 1.00 ± 0.11 1.30 ± 0.04a 1.00 ± 0.15 1.25 ± 0.08a
  1. Mean ± SEM, n = 21 to 22 mice per group. a P < 0.05 versus FVB group; b P < 0.05 versus FVB-STZ group.