Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores

Table 4 Multivariately analyzed correlation between FSSG scores and 14 background factors among 539 H₂RA users.

Factors	Regression coefficient	P-value	Standardized regression coefficient (β)
Inadequate sleep	3.280	< 0.0001 *	0.2477
Habit of midnight snack	2.830	0.0001 *	0.1595
Use of anticoagulants	-2.203	0.0493 *	-0.1056
Use of antihypertensive drugs	-1.372	0.0429 *	-0.0945
Gender (female)	1.100	0.0887	0.0816
Use of NSAIDs	-1.441	0.0805	-0.0743
Age	-0.050	0.1020	-0.0742
Habit of smoking	0.666	0.3184	0.0425
Dinner just before bedtime	0.505	0.4290	0.0359
Frequent lack of breakfast	0.483	0.5296	0.0268
BMI	0.031	0.6862	0.0173
History of cardiovascular disease	0.390	0.7445	0.0161
Habit of alcohol drinking	0.167	0.7826	0.0123
History of cerebrovascular disease	-0.030	0.9821	-0.0010

BMI, body mass index; H₂RAs, histamine H₂-receptor antagonists; NSAIDs, non-steroidal anti-inflammatory drugs. Multiple regression analysis was performed focusing on the 14 background factors, comprised of two continuous variables (age and BMI) and other 12 categorical variables. The level of significance in each factor was set at P-value < 0.05 (*). All the 14 background factors were sorted in order of absolute values of standardized regression coefficients (β).