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Table 4 Relationship between treatment workload variables and the Treatment Burden Questionnaire global score (n = 502 patients).

From: Development and description of measurement properties of an instrument to assess treatment burden among patients with multiple chronic conditions

  Correlation with the Treatment Burden Questionnaire global scorea No. (%) Mean score Pvalue
Correlation with treatment workload continuous variables
Number of hospitalizations during the last year 0.24 - - < 0.0001
Number of medical appointments/month 0.28 - - < 0.0001
Number of different physicians 0.29 - - < 0.0001
Total number of tablets/day 0.25 - - < 0.0001
Total number of injections/day 0.31 - - < 0.0001
Number of drug intakes/day 0.16 - - 0.0004
Time needed for healthcare per week (sum of the time needed for surveillance and the time needed to organize the treatment) 0.4 - - < 0.0001
Comparison between groups defined by treatment workload qualitative variables
Need for a specific organization for daily care:     
Yes - 338 (67.3%) 34.41  
No   164 (32.7%) 23.85 < 0.0001
Need for self-monitoring:     
Yes - 168 (33.5%) 41.24 < 0.0001
No   334 (66.5%) 25.79  
Diet:     
Yes - 198 (40.3%) 38.34 < 0.0001
No   293 (59.7%) 26.01  
Physical therapy:     
Yes - 113 (22.9%) 35.77  
No   380 (77.1%) 29.73 0.02
Oxygen therapy:     
Yes - 22 (4.4%) 44.68  
No   476 (94.8%) 30.47 0.005
Presence of side effects: -    
Yes   168 (36.3%) 42.07 < 0.0001
No   295 (63.7%) 25.08  
The patient considers treatment as efficient:     
Yes - 317 (63.1%) 27.35 < 0.0001
No   185 (36.8%) 37.13  
  1. Spearman correlation coefficient for continuous variables and two-sided Wilcoxon two-sample test for qualitative variables
  2. aGlobal score is the sum of all items scores of the questionnaire with 'Does not apply' and missing answers considered as the lowest possible score (0).