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Table 2 MRI protocols of the TEFR project

From: The Transeurope Footrace Project: longitudinal data acquisition in a cluster randomized mobile MRI observational cohort study on 44 endurance runners at a 64-stage 4,486km transcontinental ultramarathon

MRI in module I: Musculoskeletal System

ankle/foot (PP: FFS, supine):

• TIRM 2D sag; PM: FA 140, TE 60; TR 11320, IR 120, ST 2, SBS 2.4, FOV 900, MS 512*512, PS 0.586 iso, PB 130; IAT: 5:37

• PDw TSE fs 2D tra; PM: FA 150, TE 32, TR 5830, ST 4, SBS 4.4, FOV 256, MS 384*384, PS 0.4167 iso, PB: 150; IAT: 3:46

• syngo™ MapIt FLASH 2D sag: T2*w GRE; PM: FA 60, TE 4.5, TR 1010, ST 2.5, SBS 2.75, FOV 182.25, MS 320*320; PS 0.421875 iso, PB: 250, IN: 12; IAT: 4:15

knee (PP: FFS, supine):

• TIRM 2D sag; PM: FA 140, TE 50, TR: 4010, TI 150, ST 3, SBS 3.3, FOV 289, MS 256*256, PS 0.664 iso, PB 180; IAT: 3:31

• PDw TSE fs 2D cor; PM: FA 150, TE 31, TR 4400, ST 3, SBS 3.3, FOV 289, MS 512*512, PS 0.332 iso, PB 100; IAT: 4:11

• syngo™ MapIt FLASH 2D tra/sag: T2*w GRE; PM: FA 60, TE 4.18, TR 889/1120, ST 3, SBS 3.3, FOV 289, MS 512*512; PS 0.332 iso, PB: 250, IN: 12; IAT: 4:21/3:58

Hip (PP: FFS):

• TIRM 2D cor; PM: FA 150, TE 61, TR 6230, TI 145, ST 3.5, SBS 3.85, FOV 1444, MS 384*384, PS 0.9896 iso, PB 130; IAT: 03:38

upper/lower leg (PP: FFS, supine):

• T1w SE 2D tra, PM: FA 90, TE 13, TR 626, ST 5, SBS 5, FOV 1050/722, MS 512*336/256, PS 0.78125/0.7422 iso, PB 115; IAT: 1:54/1:30

• TIRM 2D tra; PM: FA 140, TE 62; TR 12530, TI 130, ST 3, SBS 3.9, FOV 512, MS 384*192, PS 0.833 iso, PB 180; IAT: 2:08

• PDw TSE fs 2D tra; PM: FA 150, TE 39, TR 6730, ST 3, SBS 3.9, FOV 512, MS 320*160, PS 1.0 iso, PB: 150; IAT: 2:14

• DWI (with ADC): SPAIR epi b-value 0-800, 2D tra; PM: FA 90, TE 75, TR 5100, ST 10, SBS 10, FOV 1300/1173.25, MS 128*104, PS 3.125/2.96875 iso, PB 1030; IAT: 2:32/3:01

MRI in module II: Brain and Pain

Brain (PP: HFS, supine):

• (turbo) FLASH 3D sag: T1 mpr; PM: FA 15, TE 4.75, TR 2100, ST 1, FOV 614.4, MS 240*256, PS 1.0 iso, PB130; IAT: 8:37

• T2w fs FLAIR 2D cor: TIRM; PM: FA 150, TE 120, TR 9000, TI 2500, ST 5, SBS 5.5, FOV, MS 288*384, PS 0.599 iso, PB 150; IAT: 4:43

• DWI (with ADC): SPAIR epi b-value 0-1000, 2D tra; PM: FA 90, TE 98, TR 3700, ST 5, SBS 6, FOV 529, MS 256*256, PS 0, 89844 iso, PB 1000; IAT: 0:49

functional MRI (fMRI) for pain perception: Epi 2d: epi2d_bold; PM: Fa 90, TE 60, TR 2600, ST 5, SBS 6, FOV, MS 384*384 (Start fMRI: 16*16), PS 3.59375, PB 2440; IAT: ~15:20 in total

MRI in module III: Cardiovascular System

Cardiac cine-MRI (PP: HFS, supine), IAT: ~25:00 in total

• Cine SSFP, 2D: GRE cine with retrospective 2d cardiac triggering; PM: FA 80, TE var, TR var, ST 6, SBS 6, FOV 1156/1089, MS 192*192/156, PS 1.771/1.71875 iso, PB 930, IN: 30

• Phase contrast acquisition 2D; PM: venc 150, FA 30, TE 2.33var, TR 41.1var, ST 6, FOV, MS 180*192, PS 1.875 iso, PB 555, IN:25

• Cine-tagging SSFP, 2D: GRE cine with retrospective 2d cardiac triggering; PM: FA 20, TE var, TR var, ST 6, SBS 18, FOV 1073.25, MS 212*256, PS 1.40625 iso, PB 500, IN: 21

Vascular cine-MRI (PP: HFS, supine), IAT: ~25:00 var in total

• Carotid artery: FLASH 2D tra: T2*w gradient-spoiled GRE cine with prospective 2d cardiac triggering; PM: FA 15, TE ~5.45 var, TR ~34.75 var, ST 6, FOV 289, MS 320 × 320, PS 0.53125 iso, PB 250, IN: 50/RR-cycle; IAT: ~5:30 var

• Femoral artery: FLASH 2D tra: see carotid artery; PM: FA 15, TE 5.00 var, TR 26.80 var, ST 6, FOV 768, MS 512 × 384, PS 0.625 iso, PB 250, IN: 50/RR-cycle; IAT: ~4:20 var

• Aortic flow prox./dist.: FLASH 2D tra: PM: FA 20, TE 2.75 var, TR 11.55 var, ST 5, FOV 768, MS 256*192, PS 1.25 iso, PB 590, IN: 100; IAT: ~4:10

MRI in module IV: Morphometry, Body Composition

whole body MRI (PP: HFP/FFP, prone): T1w TSE 2D tra; PM: FA 180, TE 12, TR 490, ST 10, SBS 20, FOV 1991, MS 256*196, PS 1.9922 iso, PB 120, IN: 90-120 var; IAT: appr. 20:00

MR spectroscopy (PP: FFS, supine) for evaluation of intramyocellular lipids (IMCL): Single-voxel STEAM, TE 20, TR 2000, voxel of interest 11 × 11 × 20 mm3, 40 acq., IAT: appr. 10:00

  1. Tra, transversal (axial); sag, sagittal; cor, coronal; Seq., sequence; ADC, apparent diffusion coefficient; bold, blood oxygenation level dependent contrast; DWI, diffusion weighted imaging; epi, echo planar imaging; FLAIR, fluid-attenuated inversion recovery; FLASH, fast low angle shot; fs, fat saturated; GRE, gradient echo seq.; IR, inversion recovery; mpr, MPRAGE (magnetization prepared rapid gradient echo); PDw, proton density weighting; SPAIR, spectral adiabatic inversion recovery; SSFP, steady state free precision; STEAM, stimulated-echo acquisition mode; T1w, T1 contrast; T2w, T2 contrast; TIRM, turbo inversion recovery magnitude; (T)SE, (turbo) spin echo; PM, parameters; parameter abbreviations: FA, flip angle (°); TE, time to echo (ms); TR, repetition time (ms); TI, inversion time (ms); ST, slice thickness (mm), SBS, spacing between slices (mm); FOV, field of view (cm2); MS, matrix size (pixel); PS, pixel size (mm); PB, pixel bandwith; IN, image number (n); var, variable dependency; venc, velocity encoded gradient echo imaging (cm/second); IAT, image acquisition time (min:second); PP, patient positioning; HFS, head forward supine; FFS, feet forward supine; HFP, head forward prone; FFP, feet forward prone; cardiac triggering, ECG- gating.
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BMC Medicine

ISSN: 1741-7015

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