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Table 1 Demographic data and clinical characteristics of patients with adult-onset Still's disease and healthy controls

From: Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

Characteristics

Adult-onset Still's disease (n = 24)

Healthy controls (n = 12)

Age at study entry (years)

33.3 ±9.9

32.4 ±8.2

Proportion of females

15 (62.5%)

8 (66.7%)

Fever (≥38°C)

24 (100%)

NA

Evanescent rash

20 (83.3%)

NA

Sore throat

17 (70.8%)

NA

Arthritis

15 (62.5%)

NA

Lymphadenopathy

10 (41.7%)

NA

Liver dysfunctiona

10 (41.7%)

NA

Hepatosplenomegaly

6 (25.0%)

NA

Clinical activity score

5.83 ±1.34

NA

C-reactive protein (mg/dL)

3.3 ±0.4

NA

Ferritin levels (μg/L)

692.9 ±103.6

NA

Soluble IL-2R levels (pg/mL)

563.5 ±87.5

NA

  1. Data are presented as mean ±SD or number (percentage). aLiver dysfunction was defined as alanine aminotransferase level ≧40 IU/L. NA: not applicable; IL-2R: interleukin-2 receptor.