Skip to main content
Figure 1 | BMC Medicine

Figure 1

From: Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)

Figure 1

Diindolylmethane (DIM) induces apoptosis in ovarian cancer cells. (A) SKOV-3, OVCAR-3, TOV-21G, A2780, OVCAR-429 and OVCAR-433 cells were treated with or without 50 μM or 75 μM DIM for 24 h. Cells that were positive for annexin or propidium iodide (PI) or both were measured using flow cytometry. Representative images are shown. (B) Representative western blots of cleaved caspase 3 and cleaved poly(ADP-ribose) polymerase (PARP) from the lysates collected from (i) SKOV-3, (ii) OVCAR-3, (iii) TOV-21G, (iv) A2780, (v) OVCAR-429 and (vi) OVCAR-433 cells treated with or without 75 μM DIM.

Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us