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Table 2 Age-adjusted (model I) and fully-adjusted (model II) odds ratios for medical comorbidities in men with lifetime history of mood and anxiety disorders

From: Physical comorbidities in men with mood and anxiety disorders: a population-based study

   Mood disorders Anxiety disorders
Model Odds ratio 95% CI Pvalue Odds ratio 95% CI Pvalue
Musculoskeletal disease I 1.43 (0.93 to 2.21) 0.104 1.39 (0.72 to 2.71) 0.328
II 1.47 (0.94 to 2.31) 0.092 1.70 (0.85 to 3.43) 0.135
Thyroid disorders I 1.64 (0.52 to 5.12) 0.396 5.29 (1.63 to 7.14) 0.005
II 1.81 (0.56 to 5.83) 0.321 5.54 (1.64 to 18.64) 0.006
Metabolic risk factors I 1.30 (0.85 to 1.99) 0.234 1.92 (0.96 to 3.83) 0.066
IIa 1.29 (0.83 to 2.00) 0.265 2.20 (1.07 to 4.53) 0.032
GORD I 2.41 (1.48 to 3.00) <0.001 3.84 (2.01 to 7.33) <0.001
II 2.67 (1.60 to 4.47) <0.001 4.25 (2.18 to 8.26) <0.001
Gastrointestinal disorders I 1.47 (0.93 to 2.30) 0.096 2.22 (1.20 to 4.10) 0.011
II 1.46 (0.91 to 2.34) 0.112 2.40 (1.28 to 4.50) 0.006
Recurrent headaches I 2.46 (1.29 to 4.69) 0.007 0.63 (0.15 to 2.69) 0.537
II 2.53 (1.30 to 4.96) 0.007 0.67 (0.16 to 2.89) 0.592
Syncope and seizures I 2.01 (1.31 to 3.09) 0.002 1.46 (0.75 to 2.85) 0.263
II 2.01 (1.28 to 3.16) 0.002 1.55 (0.78 to 3.07) 0.207
Cardiovascular disease I 1.27 (0.82 to 1.93) 0.292 1.93 (0.60 to 2.13) 0.708
II 1.28 (0.82 to 2.01) 0.276 1.15 (0.59 to 2.25) 0.678
Pulmonary disease All I - - - 0.95 (0.48 to 1.86) 0.874
II - - - 1.02 (0.51 to 2.03) 0.956
<60 years old I 0.90 (0.52 to 1.58) 0.725 - - -
II 1.01 (0.57 to 1.79) 0.971 - - -
≥60 years old I 2.75 (1.45 to 5.21) 0.002 - - -
II 2.65 (1.34 to 5.21) 0.005 - - -
Liver disorders I 2.64 (1.40 to 4.98) 0.003 0.97 (0.29 to 3.24) 0.964
II 3.03 (1.57 to 5.83) 0.001 1.03 (0.30 to 3.46) 0.967
Cancer I 0.95 (0.56 to 1.61) 0.839 1.03 (0.47 to 2.29) 0.933
II 0.90 (0.52 to 1.56) 0.706 1.03 (0.46 to 2.32) 0.938
Psoriasis I 1.63 (0.75 to 3.55) 0.219 2.44 (0.91 to 6.57) 0.076
II 1.41 (0.51 to 2.91) 0.648 2.77 (1.00 to 7.67) 0.049
High medical burden I 1.80 (1.16 to 2.77) 0.008 2.82 (1.43 to 5.53) 0.003
IIa 1.86 (1.19 to 2.91) 0.007 3.23 (1.61 to6.47) 0.001
  1. aModel not adjusted for BMI as it is recorded in the medical condition. Model I – Age-adjusted; Model II – Fully-adjusted including: age, BMI, SES, physical activity, smoking and alcohol consumption. BMI, body mass index; CI, confidence interval; GORD, gastro oesaphogeal reflux disease; SES, socioeconomic status.