Targeted rotavirus vaccination of high-risk infants; a low cost and highly cost-effective alternative to universal vaccination

Table 5 Mean costs per different health outcome comparing different RV vaccination strategies under base-case assumptions (RV1) using a healthcare provider perspective

	Targeted versus no vaccination	Universal versus no vaccination	Universal versus targeted vaccination
Costs (€) ^a
per case avoided	21	174	191
per life year saved	2,400	96,600	894,000
per fatal case	0.03^b	1.03^b	21.60^b
per QALY gained	2,600	60,200	162,000

^aA discount rate of 3% was used for both costs and effects; ^b€million. QALY, quality-adjusted life year; RV, rotavirus.

ISSN: 1741-7015