From: Immunity, atherosclerosis and cardiovascular disease
Treatment
Targets
Statins [102–105].
Prenylation, oxidation, MHC-class II presentation
Phospholipase-inhibitors [113] Annexin A5 [112]. Anti-PC [37, 39, 40, 42–44].
Oxidized phospholipids
Anti-apoB [115–117].
apoB
Cytokine-inhibition [105, 110]
Interleukin-1ß/Inflammasome
Metotrexate [105–107]
Inhibition of purine metabolism
Active immunization [40, 114, 115, 121]
oxLDL, apoB, PC- epitopes, HSP
