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Table 2 Research domain criteria, October 2012 (constructs are listed within each domain)

From: Toward the future of psychiatric diagnosis: the seven pillars of RDoC

Negative valence domain

Positive valence systems

Cognitive systems

Systems for social processes

Arousal/modulatory systems

Acute threat (‘fear’)

Approach motivation

Attention

Affiliation and attachment

Arousal

Potential threat (‘anxiety’)

Initial responsiveness to reward

Perception

Social communication

Biological rhythms

Sustained threat

Sustained responsiveness to reward

Working memory

Perception and understanding of self

Sleep-wake

Loss

Reward learning

Declarative memory

Perception and understanding of others

 

Frustrative nonreward

Habit

Language behavior

  
  

Cognitive (effortful) control

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