Table 1 Meta-analyses examining the association between depression and incidence of mortality or morbidity in disease-free subjects
Incident event | Reference | Nr studies included | Nr subjects included | Pooled risk (95% CI) of depression |
|---|---|---|---|---|
Overall mortality | Cuijpers et al.[5] | 25 | 106,628 | 1.81 (1.58 to 2.07) |
Heart disease | Nicholson et al. [3] | 21 | 124,509 | 1.81 (1.53 to 2.15) |
Hypertension | Meng et al. [12] | 9 | 22,367 | 1.42 (1.09 to 1.86) |
Stroke | Dong et al. [13] | 17 | 206,641 | 1.34 (1.17 to 1.54) |
Diabetes | Mezuk et al. [4] | 13 | 212,019 | 1.60 (1.37 to 1.88) |
Alzheimer’s disease | Gao et al. [14] | 4 | 5,656 | 1.66 (1.29 to 2.14) |
Obesity (BMI ≥30) | Luppino et al. [15] | 9 | 6,436 | 1.58 (1.33 to 1.81) |
Cancer | Chida et al. [16] | 25 | n.a. | 1.29 (1.14 to 1.46) |