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Table 2 Impact of immediate vs deferred initiation of antiretroviral therapy (ART) on mortality: data from randomized controlled trials involving ART-naïve HIV+ persons

From: When to start antiretroviral therapy: the need for an evidence base during early HIV infection

Study (reference) Deaths, early ART initiationaarm Deaths, deferred ART initiationbarm
SMART [29] 0/131 1/118
CIPRA HT-001 [30] 6/408 23/408
HPTN 052 [9] 10/886 13/877
Pooled data from the three trials 16/1,425 37/1,403
  1. aEarly ART initiation defined as start of ART at CD4 >350 cells/μl.
  2. bDeferred ART initiation defined as start of ART at CD4 <200 or <250 cells/μl.