|
Sample/group
|
25-OH D
|
Total
|
Downstream
|
Exons
|
Intergenic
|
Introns
|
Up and downstream
|
Upstream
|
UTR
|
|---|
| | |
Number
|
%
|
|---|
|
High 25-hydroxyvitamin D
|
≥75
|
13,054
|
5.3
|
4.0
|
32.8
|
28.4
|
4.7
|
14.6
|
10.2
|
|
Low 25-hydroxyvitamin D
|
<75
|
1,526
|
3.7
|
4.8
|
36.5
|
18.6
|
4.3
|
18.8
|
13.3
|
|
1_VDR
|
80
|
3,073
|
5.2
|
3.9
|
37.9
|
24.0
|
4.7
|
13.8
|
10.5
|
|
2_VDR
|
107
|
7,118
|
5.6
|
4.5
|
28.2
|
26.3
|
5.1
|
17.0
|
13.2
|
|
3_VDR
|
76
|
5,290
|
5.4
|
3.5
|
36.8
|
29.1
|
4.1
|
12.9
|
8.3
|
|
4_VDR
|
85
|
3,059
|
5.1
|
4.0
|
37.3
|
22.3
|
4.7
|
15.6
|
11.0
|
|
5_VDR
|
75
|
4,051
|
4.6
|
4.8
|
33.0
|
21.5
|
5.3
|
18.8
|
12.1
|
|
HB
|
29
|
1,021
|
3.5
|
5.7
|
27.4
|
16.9
|
5.6
|
24.1
|
17.0
|
|
PD
|
32
|
200
|
1.0
|
3.0
|
61.7
|
21.4
|
0.5
|
7.0
|
5.5
|
|
SP
|
34
|
610
|
3.2
|
4.5
|
38.7
|
18.8
|
3.7
|
18.3
|
13.0
|
|
SR
|
22
|
573
|
3.5
|
4.9
|
39.7
|
17.7
|
4.0
|
18.5
|
11.7
|
|
r
| |
0.92
|
0.82
|
−0.22
|
−0.40
|
0.79
|
0.44
|
−0.14
|
−0.05
|
|
P
| |
0.0005
|
0.0068
|
0.5746
|
0.2822
|
0.0115
|
0.2401
|
0.7163
|
0.891
|
- The number of VDR binding sites at FDR <0.1%. 25-hydroxyvitamin D (25(OH)D) levels are shown in nM. Correlations are shown between 25(OH)D and the number of binding sites. VDR, vitamin D receptor.
