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Table 1 Number of VDR binding sites

From: Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

Sample/group 25-OH D Total Downstream Exons Intergenic Introns Up and downstream Upstream UTR
   Number %
High 25-hydroxyvitamin D ≥75 13,054 5.3 4.0 32.8 28.4 4.7 14.6 10.2
Low 25-hydroxyvitamin D <75 1,526 3.7 4.8 36.5 18.6 4.3 18.8 13.3
1_VDR 80 3,073 5.2 3.9 37.9 24.0 4.7 13.8 10.5
2_VDR 107 7,118 5.6 4.5 28.2 26.3 5.1 17.0 13.2
3_VDR 76 5,290 5.4 3.5 36.8 29.1 4.1 12.9 8.3
4_VDR 85 3,059 5.1 4.0 37.3 22.3 4.7 15.6 11.0
5_VDR 75 4,051 4.6 4.8 33.0 21.5 5.3 18.8 12.1
HB 29 1,021 3.5 5.7 27.4 16.9 5.6 24.1 17.0
PD 32 200 1.0 3.0 61.7 21.4 0.5 7.0 5.5
SP 34 610 3.2 4.5 38.7 18.8 3.7 18.3 13.0
SR 22 573 3.5 4.9 39.7 17.7 4.0 18.5 11.7
r   0.92 0.82 −0.22 −0.40 0.79 0.44 −0.14 −0.05
P   0.0005 0.0068 0.5746 0.2822 0.0115 0.2401 0.7163 0.891
  1. The number of VDR binding sites at FDR <0.1%. 25-hydroxyvitamin D (25(OH)D) levels are shown in nM. Correlations are shown between 25(OH)D and the number of binding sites. VDR, vitamin D receptor.