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Table 1 Study populations, inputs, and outcomes used to construct each of the risk scores used in this study

From: Comparative assessment of absolute cardiovascular disease risk characterization from non-laboratory-based risk assessment in South African populations

Score

Populationa

Inputs

Outcome

Non-laboratory-based (Gaziano et al., 2008) [8]

NHANES I (US, 1971 to 1975)

Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, BMI

CVD death, MI, stroke, CHF, coronary bypass, PTCA

Framingham CVD 2008 (D’Agostino et al., 2008) [11]

Framingham, MA, US (1968 to 1987)

Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, total cholesterol, HDL cholesterol

MI, angina, coronary insufficiency, CHD death, stroke, TIA, CHF, PVD, CVD death

Framingham CVD (Anderson et al., 1991) [10]

Framingham, MA, (US., 1968 to 1975)

Age, sex, smoking, diabetes, systolic blood pressure, total cholesterol, HDL cholesterol

Same as above

Framingham CHD (Anderson et al., 1991) [10]

Same as above

Same as above

MI, CHD death, angina, coronary insufficiency

SCORE, high risk (Conroy et al., 2003) [4]

High risk European countriesb

Age, sex, smoking, systolic blood pressure, total cholesterol

Death from: hypertensive disease, IHD, cerebrovascular disease

SCORE, low risk (Conroy et al., 2003) [4]

Low risk European countriesc

Same as above

Same as above

CUORE (Giampaoli et al., 2007) [12]

Italy (1983 to 1997)

Age, sex, smoking, diabetes, systolic blood pressure, treatment for hypertension, total cholesterol, HDL cholesterol

Fatal and non-fatal MI or stroke

  1. aYears indicate when baseline values were collected; bapplicable for all non-low risk European countries; capplicable for Belgium, France, Greece, Italy, Luxembourg, Portugal, Spain, and Switzerland. BMI, body-mass index; CHD coronary heart disease, CHF congestive heart failure, CVD cardiovascular disease, HDL high-density lipoprotein, IHD ischemic heart disease, MI myocardial infarction, NHANES National Health and Nutrition Examination Survey, PTCA percutaneous transluminal coronary angioplasty, PVD peripheral vascular disease, TIA transient ischemic attack.