Comparative assessment of absolute cardiovascular disease risk characterization from non-laboratory-based risk assessment in South African populations

Table 6 Risk categorization results for six laboratory-based risk scores, each compared to non-laboratory-based risk score, men ^a

Dataset	Number	Fr_CVD_08	Fr_CVD_91	Fr_CHD_91	SCORE_h	SCORE_l	CUORE
Aggregate	5,751	89.8%	91.0%	86.4%	95.2%	95.6%	92.5%
BRISK	287	97.9%	97.2%	97.2%	99.3%	99.3%	97.9%
CRIBSA	357	93.3%	92.2%	91.6%	93.3%	93.8%	95.0%
Mangaung	276	90.5%	91.3%	85.5%	95.6%	95.6%	93.5%
QwaQwa	247	94.3%	94.3%	91.0%	97.6%	96.7%	95.9%
AHA-FS Urban	90	88.9%	91.1%	86.7%	93.3%	95.6%	95.6%
AHA-FS Rural	151	85.6%	84.9%	78.1%	94.5%	94.5%	90.4%
PURE, Urban	364	95.7%	95.7%	92.1%	97.6%	97.6%	97.0%
PURE, Rural	326	90.1%	90.7%	88.9%	95.1%	95.1%	90.7%
KwaZulu-Natal	130	87.6%	84.5%	81.4%	93.8%	92.2%	92.2%
CRISIC	382	96.9%	96.6%	94.8%	98.7%	99.0%	97.7%
Mamre	296	94.6%	93.2%	89.8%	96.6%	96.6%	95.3%
KORIS	2,571	90.9%	91.8%	88.0%	95.6%	96.0%	93.5%
Phoenix	274	92.7%	91.2%	86.1%	90.5%	90.5%	94.9%
Aggregate^b		92.1%	93.0%	89.6%	95.5%	95.9%	94.2%

^a‘Agreement’ based on dichotomous risk categorization corresponding to 10-year Framingham (2008) CVD risk >20%, unless otherwise noted. For SCORE this is equivalent to a 5% fatal CVD risk; ^bthreshold of 10-year Framingham CHD risk >20%. CHD coronary heart disease, CVD cardiovascular disease, Fr Framingham.

ISSN: 1741-7015