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Table 2 PTH, immunoglobulins and complement C4 and C3 levels compared among four concentration ranges of 25(OH)D in 1,291 healthy older subjects

From: Serum concentrations of 25-hydroxyvitamin D and immunoglobulins in an older Swiss cohort: results of the Senior Labor Study

Analyte

25(OH)D

 

<10

10 to 20

21 to 29

≥30

P-value

 

N = 103

N = 403

N = 404

N = 381

  
     

Trend

Sd/Nor+

PTH

7.87 ± 0.51*

4.78 ± 0.13

4.25 ± 0.10

3.73 ± 0.10

<0.01

<0.01

pg/ml

IgA

2.32 ± 0.10

2.12 ± 0.05

2.22 ± 0.05

2.12 ± 0.05

0.12

0.036

mg/ml

IgE

145.38 ± 50.1

75.45 ± 10.08

85.01 ± 13.17

70.37 ± 7.89

0.28

>0.05

kU/l

IgM

0.88 ± 0.05

0.94 ± 0.04

0.96 ± 0.03

0.98 ± 0.03

0.09

>0.05

mg/ml

IgG

10.63 ± 0.25

10.05 ± 0.11

10.28 ± 0.10

10.28 ± 0.12

0.24

>0.05

mg/ml

IgG1

6.74 ± 0.21

6.16 ± 0.08

6.17 ± 0.07

6.41 ± 0.11

0.14

0.033

mg/ml

IgG2

3.13 ± 0.15

3.23 ± 0.07

3.45 ± 0.07

3.24 ± 0.06

0.01

>0.05

mg/ml

IgG3

0.38 ± 0.02

0.37 ± 0.01

0.38 ± 0.01

0.41 ± 0.03

0.37

>0.05

mg/ml

IgG4

0.66 ± 0.06

0.60 ± 0.03

0.66 ± 0.03

0.59 ± 0.02

0.12

>0.05

mg/ml

C4

0.22 ± 0.01

0.23 ± 0.00

0.23 ± 0.00

0.23 ± 0.00

0.02

0.01

mg/ml

C3

1.11 ± 0.02

1.09 ± 0.01

1.7 ± 0.007

1.07 ± 0.01

0.03

0.01

mg/ml

      
  1. * Mean ± 1 SD.
  2. +Sd/Nor: between the groups of Severely deficient and Normal serum concentrations of 25(OH)D.
  3. Differences between groups were assessed by Kruskal-Wallis test.