Figure 2From: Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease Schematic illustration of the frequent exacerbator phenotype. While many patients with chronic obstructive pulmonary disease (COPD) experience exacerbations, there is a subgroup of patients who enter a destructive cycle of frequent exacerbations with associated poorer outcome. This phenotype appears to be maintained over time.Back to article page