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Table 2 Multivariate-adjusted odds ratios (95% CIs) a for associations between total intakes of vitamin D and magnesium and risk of vitamin D deficiency and insufficiency, National Health and Nutrition Examination Survey (NHANES) 2001 to 2006

From: Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III

Nutrient intakes

Controls, N

Deficiency

Insufficiency

N

OR (95% CI)

N

OR (95% CI)

Total vitamin D intake (IU/day)

     

 Q1 <114

1,741

1,005

1.00

1,450

1.00

 Q2 114 to 307

1,740

446

0.55 (0.40 to 0.75)

1,086

0.75 (0.62 to 0.91)

 Q3 308 to 539

1,741

152

0.22 (0.15 to 0.34)

665

0.55 (0.44 to 0.69)

 Q4 ≥540

1,740

72

0.10 (0.06 to 0.17)

419

0.37 (0.27 to 0.51)

 P for trend

  

<0.001

 

<0.001

Dietary vitamin D intake (IU/day) 

    

 Q1 <57.8

1,741

764

1.00

1,183

1.00

 Q2 57.8 to 137

1,740

468

0.71 (0.55 to 0.91)

997

0.86 (0.71 to 1.05)

 Q3 138 to 261

1,741

279

0.54 (0.40 to 0.72)

807

0.72 (0.59 to 0.88)

 Q4 ≥262

1,740

164

0.29 (0.20 to 0.41)

633

0.69 (0.56 to 0.86)

 P for trend

  

<0.001

 

<0.001

Supplemental vitamin D intake (IU/day) 

    

 Non-user

3,704

1,473

1.00

2,602

1.00

 1 to 239

809

93

0.32 (0.20 to 0.50)

377

0.84 (0.68 to 1.03)

 240 to 399

331

19

0.29 (0.13 to 0.64)

109

0.57 (0.38 to 0.87)

 ≥400

2,118

90

0.19 (0.11 to 0.33)

532

0.40 (0.29 to 0.53)

 P for trend

  

<0.001

 

<0.001

Total magnesium intake (mg/day)

     

 Q1 <225

1,749

876

1.00

1,362

1.00

 Q2 225 to 310

1,733

392

0.67 (0.50 to 0.90)

907

0.78 (0.61 to 1.00)

 Q3 311 to 419

1,737

245

0.43 (0.30 to 0.63)

758

0.73 (0.59 to 0.89)

 Q4 ≥420

1,743

162

0.34 (0.21 to 0.56)

593

0.62 (0.46 to 0.82)

 P for trend

  

<0.001

 

<0.001

Dietary magnesium intake (mg/day) 

    

 Q1 <195

1,754

726

1.00

1,255

1.00

 Q2 195 to 268

1,732

432

0.75 (0.58 to 0.97)

893

0.75 (0.62 to 0.90)

 Q3 269 to 363

1,741

297

0.68 (0.47 to 0.99)

777

0.69 (0.55 to 0.87)

 Q4 ≥364

1,735

220

0.43 (0.26 to 0.70)

695

0.61 (0.45 to 0.83)

 P for trend

  

0.002

 

0.002

Supplemental magnesium intake (mg/day) 

    

 Non-user

3,922

1,440

1.00

2,548

1.00

 1 to 49

669

109

0.53 (0.34 to 0.81)

334

1.14 (0.91 to 1.43)

 50 to 99

506

43

0.35 (0.17 to 0.71)

205

0.80 (0.53 to 1.22)

 ≥100

1,865

83

0.30 (0.17 to 0.52)

533

0.68 (0.52 to 0.88)

 P for trend

  

<0.001

 

0.008

  1. aSurvey logistic regression models used to estimate odds ratios and 95% confidence intervals. Models adjusted for age, sex, body mass index (BMI), educational attainment, race, household income, smoking status, alcohol use, physical activity, month of blood collection, dietary intakes of total energy and total calcium intake. Models were also adjusted for total intake of vitamin D or magnesium mutually.