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Table 2 Commercially available LPAs for TB detection in clinical specimens

From: Rapid diagnostics of tuberculosis and drug resistance in the industrialized world: clinical and public health benefits and barriers to implementation

Assay Manufacturer Method Material Sensitivity,% (95% CI) Specificity,% (95% CI) References
INNO-LiPA Rif.TB InnoGenetics, Gent, Belgium PCR amplification/hybridization DNA from decontaminated smear-positive sputum 93.0 (92.0 to 94.0) 83.0 (81.0 to 85.0) [29, 30]
INNO-LiPA Rif.TB InnoGenetics, Gent, Belgium PCR amplification/hybridization DNA from decontaminated smear-negative sputum 65.0 (58.0 to 71.0) 96.0 (94.0 to 97.0) [2932]
Hain GT MTBDRplus Hain Lifescience GbmH, Nehren, Germany PCR amplification/hybridization DNA from decontaminated sputum 92.0 (90.0 to 94.0) - [33, 34]
  1. CI, confidence interval; LPA, line-probe assay.