From: Associations between smoking, components of metabolic syndrome and lipoprotein particle size
Smoking status | Men | Women | ||||||
---|---|---|---|---|---|---|---|---|
 | Non-smoker | Former smoker | Current smoker | Pvalue | Non-smoker | Former smoker | Current smoker | Pvalue |
n (%) | 10,529 (43.2%) | 8,175 (33.5%) | 5,685 (23.3%) | Â | 16,456 (46.9%) | 11,633 (33.2%) | 6,989 (19.9%) | Â |
Age, years | 42 ± 11 | 51 ± 12 | 43 ± 11 | <0.001 | 43 ± 12 | 48 ± 11 | 42 ± 11 | <0.001 |
BMI, kg/m2 | 26.1 ± 3.7 | 27.0 ± 3.5 | 26.2 ± 3.7 | <0.001 | 25.6 ± 4.8 | 26.3 ± 4.7 | 25.4 ± 4.6 | <0.001 |
BMI ≥30 kg/m2, n (%) | 1,311 (12.5%) | 1,390 (17.0%) | 812 (14.3%) |  | 2,623 (15.9%) | 2,087 (17.9%) | 951 (13.6%) |  |
SBP, mmHg | 130 ± 13 | 133 ± 14 | 131 ± 13 | <0.001 | 122 ± 15 | 124 ± 16 | 121 ± 14 | <0.001 |
DBP, mmHg | 76 ± 9 | 78 ± 9 | 76 ± 9 | <0.001 | 72 ± 9 | 73 ± 9 | 72 ± 9 | <0.001 |
Total cholesterol, mmol/l | 5.0 ± 1.0 | 5.2 ± 1.0 | 5.1 ± 1.0 | <0.001 | 4.9 ± 1.0 | 5.1 ± 1.0 | 5.0 ± 1.0 | <0.001 |
LDL-C, mmol/l | 3.28 ± 0.86 | 3.43 ± 0.89 | 3.39 ± 0.92 | <0.001 | 2.99 ±0.85 | 3.18 ± 0.89 | 3.14 ± 0.92 | <0.001 |
HDL-C, mmol/l | 1.31 ± 0.31 | 1.31 ± 0.32 | 1.21 ± 0.30 | <0.001 | 1.59 ± 0.38 | 1.65 ± 0.40 | 1.49 ± 0.38 | <0.001 |
Triglycerides, mmol/la | 1.12 (0.78 to 1.54) | 1.25 (0.87 to 1.73) | 1.35 (0.92 to 1.91) | <0.001 | 0.87 (0.64 to 1.16) | 0.93 (0.68 to 1.25) | 1.01 (0.73 to 1.36) | <0.001 |
Apolipoprotein A1, g/l | 1.43 ± 0.22 | 1.46 ± 0.22 | 1.40 ± 0.22 | <0.001 | 1.61 ± 0.27 | 1.66 ± 0.27 | 1.57 ± 0.28 | <0.001 |
HDL-C/apoA1 ratio | 0.89 ± 0.13 | 0.88 ± 0.13 | 0.85 ± 0.13 | <0.001 | 0.97 ± 0.14 | 0.98 ± 0.60 | 0.92 ± 0.13 | <0.001 |
Apolipoprotein B, g/l | 0.94 ± 0.23 | 1.00 ± 0.24 | 1.00 ± 0.25 | <0.001 | 0.87 ± 0.23 | 0.91 ± 0.23 | 0.93 ± 0.24 | <0.001 |
LDL-C/apoB ratio | 3.49 ± 0.37 | 3.45 ± 0.41 | 3.37 ± 0.40 | <0.001 | 3.44 ± 0.37 | 3.47 ± 0.36 | 3.38 ± 0.36 | <0.001 |
Blood glucose, mmol/la | 5.05 (4.70 to 5.30) | 5.26 (4.90 to 5.50) | 5.11 (4.70 to 5.40) | <0.001 | 4.83 (4.50 to 5.10) | 4.94 (4.60 to 5.20) | 4.84 (4.50 to 5.10) | <0.001 |
Waist circumference, cm | 94 ± 11 | 98 ± 10 | 95 ± 11 | <0.001 | 86 ± 12 | 89 ± 12 | 87 ± 12 | <0.001 |
BP-lowering medication, n (%) | 821 (7.8%) | 1,497 (18.3%) | 503 (8.8%) | <0.001 | 1,683 (10.2%) | 1,660 (14.3%) | 621 (8.9%) | <0.001 |
Statin use, n (%) | 411 (3.9% | 918 (11.2% | 419 (7.4%) | <0.001 | 560 (3.4%) | 594 (5.1%) | 275 (3.9%) | <0.001 |
TG-lowering medication, n (%) | 13 (0.1%) | 24 (0.3%) | 14 (0.2%) | NS | 6 (0.1%) | 10 (0.1%) | 6 (0.1%) | NS |
Type 2 diabetes, n (%) | 113 (1.1%) | 264 (3.2%) | 83 (1.5%) | <0.001 | 188 (1.1%) | 216 (1.9%) | 68 (1.0%) | NS |
Oral antihyperglycemic medication, n (%) | 102 (1.0%) | 217 (2.7%) | 69 (1.2%) | <0.001 | 154 (0.9%) | 164 (1.4%) | 55 (0.8%) | <0.001 |