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Table 4 Similarities in autoimmune responses between encephalomyelitis disseminata/multiple sclerosis (ED/MS) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

From: Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

Autoimmune responses ED/MS ME/CFS
Increased numbers of B cells
Anti-nuclear antibodies
Anti-cardiolipin antibodies
Anti-phospholipid antibodies
Anti-neuronal antibodies
Anti-muscle antibodies
Anti-ganglioside antibodies
Anti-serotonin (5-hydroxytryptamine (5-HT)) antibodies
Anti-muscarinic cholinergic receptor antibodies -
Anti-mu-opioid antibodies -
Anti-5-HTA receptor antibodies -
Anti-D2 receptor antibodies -
IgM against oxidatively modified neoepitopes, for example, malondialdehyde, oleic and myristic and palmitic acid
IgM against nitrosatively modified neoepitopes, for example, NO adducts
Response to rituximab