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Table 2 Mean differences in BP changes (mmHg) in the two intervention groups versus the control group after 4 years of follow-up (median follow-up 3.8 years)

From: Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial

  MD+EVOO versus control Pvalue MD+nuts versus control Pvalue
Systolic BP     
 Crude model 0.42 (−0.46 to 1.30) 0.35 −0.90 (−1.77 to −0.03) 0.04
 Multivariate-adjusted 1a 0.40 (−0.46 to 1.27) 0.36 −0.73 (−1.58 to 0.13) 0.10
 Multivariate-adjusted 2b 0.41 (−0.46 to 1.28) 0.35 −0.72 (−1.57 to 0.13) 0.10
 Multivariate-adjusted 3c 0.39 (−0.48 to 1.26) 0.38 −0.72 (−1.58 to 0.13) 0.10
Diastolic BP     
 Crude model −1.41 (−1.92 to −0.91) <0.001 −0.61 (−1.12 to −0.09) 0.02
 Multivariate-adjusted 1a −1.49 (−1.98 to −1.00) <0.001 −0.65 (−1.15 to −0.14) 0.01
 Multivariate-adjusted 2b −1.49 (−1.97 to −1.00) <0.001 −0.64 (−1.15 to −0.14) 0.01
 Multivariate-adjusted 4d −1.53 (−2.01 to −1.04) <0.001 −0.65 (−1.15 to −0.15) 0.01
  1. BP, blood pressure; MD+EVOO, Mediterranean diet plus extra virgin olive oil; MD+nuts, Mediterranean diet plus nuts.
  2. aAdjusted for center, age, sex and diabetes.
  3. bMultivariate-adjusted 1 + additional adjustment for number of baseline anti-hypertensive drugs.
  4. cMultivariate-adjusted 2 + additional adjustment for baseline systolic BP.
  5. dMultivariate-adjusted 2 + additional adjustment for baseline diastolic BP.