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Table 2 Mean differences in BP changes (mmHg) in the two intervention groups versus the control group after 4 years of follow-up (median follow-up 3.8 years)

From: Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial

 

MD+EVOO versus control

Pvalue

MD+nuts versus control

Pvalue

Systolic BP

    

 Crude model

0.42 (−0.46 to 1.30)

0.35

−0.90 (−1.77 to −0.03)

0.04

 Multivariate-adjusted 1a

0.40 (−0.46 to 1.27)

0.36

−0.73 (−1.58 to 0.13)

0.10

 Multivariate-adjusted 2b

0.41 (−0.46 to 1.28)

0.35

−0.72 (−1.57 to 0.13)

0.10

 Multivariate-adjusted 3c

0.39 (−0.48 to 1.26)

0.38

−0.72 (−1.58 to 0.13)

0.10

Diastolic BP

    

 Crude model

−1.41 (−1.92 to −0.91)

<0.001

−0.61 (−1.12 to −0.09)

0.02

 Multivariate-adjusted 1a

−1.49 (−1.98 to −1.00)

<0.001

−0.65 (−1.15 to −0.14)

0.01

 Multivariate-adjusted 2b

−1.49 (−1.97 to −1.00)

<0.001

−0.64 (−1.15 to −0.14)

0.01

 Multivariate-adjusted 4d

−1.53 (−2.01 to −1.04)

<0.001

−0.65 (−1.15 to −0.15)

0.01

  1. BP, blood pressure; MD+EVOO, Mediterranean diet plus extra virgin olive oil; MD+nuts, Mediterranean diet plus nuts.
  2. aAdjusted for center, age, sex and diabetes.
  3. bMultivariate-adjusted 1 + additional adjustment for number of baseline anti-hypertensive drugs.
  4. cMultivariate-adjusted 2 + additional adjustment for baseline systolic BP.
  5. dMultivariate-adjusted 2 + additional adjustment for baseline diastolic BP.