Figure 3

Transgenerational obesity and associated disease. Percentages of the F1 and F3 generation disease/abnormalities from control (open bars), dichlorodiphenyltrichloroethane (DDT) (black bars) and lower dose (LD) DDT lineages. Testis disease (a), spermatogenic cell apoptosis (b) and sperm counts (c), ovarian disease (d), polycystic ovarian disease (e) and primordial follicle pool loss (f) are presented. Percentages of females (g) and males (h) with kidney diseases and percentages of females (I) and males (J) with incidence of multiple disease. The number of diseased rats/total number of rats (n value) is shown above the respective bar graphs. Those showing numbers above the bars were analyzed with a logistic regression analysis and those with a mean ± SEM indicated were analyzed with a t test with the P value indicated (*P <0.05; **P <0.01; ***P <0.001) (Additional file 4: Table S2 and Additional file 5: Table S3).