Table 7 Summary of all tests evaluated

Symptoms

Kim et al. [24]

NCCP with atypical GERD symptoms

Endoscopy (LA classification) and/or 24 h pH-metry (>4%, pH <4

3

20

5

6

0.38

0.23

0.13

0.55

0.49

2.71

24

13

45

Kim et al. [24]

NCCP with typical GERD symptoms

Endoscopy (LA classification) and/or 24 h pH-metry (>4%, pH <4

11

2

5

6

0.69

0.75

0.85

0.55

2.75

0.42

67

85

45

Mousavi et al. [27]

NCCP with typical GERD symptoms

GERD if two tests positive: endoscopy (Hentzel-Dent), Bernstein test, omeprazole trial

11

5

24

38

0.31

0.88

0.69

0.61

2.70

0.78

45

69

39

Mousavi et al. [27]

NCCP relieved by antacid

GERD if two tests positive: endoscopy (Hentzel-Dent), Bernstein test, omeprazole trial

15

36

20

7

0.43

0.16

0.68

0.64

0.51

3.51

45

29

74

Mousavi et al. [27]

NCCP and heartburn in history

GERD if two tests positive: endoscopy (Hentzel-Dent), Bernstein test, omeprazole trial

14

8

21

35

0.40

0.81

0.64

0.63

2.15

0.74

45

64

38

Mousavi et al. [27]

NCCP and regurgitation in history

GERD if two tests positive: endoscopy (Hentzel-Dent), Bernstein test, omeprazole trial

17

7

18

36

0.49

0.84

0.71

0.67

2.98

0.61

45

71

33

Hong et al. [25]

NCCP

Manometry (Specler 2001 criteria) and/or 24 h pH-metry (>4% pH <4)

72

114

128

148

0.36

0.56

0.39

0.54

0.83

1.13

43

39

46

Hong et al. [25]

Control: dysphagia

Manometry (Specler 2001 criteria) and/or 24 h pH-metry (>4% pH <4)

27

26

181

228

0.13

0.90

0.51

0.56

1.27

0.97

45

51

44

Hong et al. [25]

Control: GERD-typical symptoms

Manometry (Specler 2001 criteria) and/or 24 h pH-metry (>4% pH <4)

53

53

151

205

0.26

0.79

0.50

0.58

1.26

0.93

44

50

42

Hong et al. [25]

Dysphagia

Manometry

16

37

84

325

0.16

0.90

0.30

0.80

1.57

0.94

22

30

21

Hong et al. [25]

Dysphagia

24 h pH-metry

4

49

63

346

0.06

0.88

0.08

0.85

0.48

1.07

15

8

15

Hong et al. [25]

Dysphagia

Manometry and 24 h pH-metry

7

46

23

386

0.23

0.89

0.13

0.94

2.19

0.86

7

13

6

Hong et al. [25]

NCCP

Manometry

34

152

63

213

0.35

0.58

0.18

0.77

0.84

1.11

21

18

23

Hong et al. [25]

NCCP

24 h pH-metry

29

157

43

233

0.40

0.60

0.16

0.60

1.00

1.00

16

16

16

Hong et al. [25]

NCCP

Manometry and 24 h pH-metry

9

177

22

254

0.29

0.59

0.05

0.92

0.71

1.20

7

5

8

Hong et al. [25]

GERD-typical symptoms

Manometry

19

87

81

275

0.19

0.76

0.18

0.77

0.79

1.07

22

18

23

Hong et al. [25]

GERD-typical symptoms

24 h pH-metry

23

83

49

307

0.32

0.79

0.22

0.86

1.50

0.86

16

22

14

Hong et al. [25]

GERD-typical symptoms

Manometry and 24 h pH-metry

11

95

20

336

0.35

0.78

0.10

0.94

1.61

0.83

7

10

6

Netzer et al. [26]

NCCP

Manometry and/or 24 h pH-metry (>10.5% pH <4)

31

14

223

35

0.12

0.71

0.69

0.14

0.43

1.23

84

69

86

Netzer et al. [26]

Control: GERD-typical symptoms

Manometry and/or 24 h pH-metry (>10.5% pH <4)

127

16

127

33

0.50

0.67

0.89

0.21

1.53

0.74

84

89

79

Netzer et al. [26]

Control: dysphagia

Manometry and/or 24 h pH-metry (>10.5% pH <4)

48

8

206

41

0.19

0.84

0.86

0.17

1.16

0.97

84

86

83

Netzer et al. [26]

GERD-typical symptoms

24 h pH-metry

115

28

49

111

0.70

0.80

0.80

0.69

3.48

0.37

54

80

31

Netzer et al. [26]

Dysphagia

24 h pH-metry

6

50

158

89

0.04

0.64

0.11

0.36

0.10

1.50

54

11

64

Netzer et al. [26]

NCCP

24 h pH-metry

24

21

140

118

0.15

0.85

0.53

0.46

0.97

1.01

54

53

54

PPI trial

Dickman et al. [31]

Rabeprazole 20 mg twice a day for 1 week SIS ≥50%

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

12

2

4

17

0.75

0.89

0.86

0.81

7.13

0.28

46

86

19

Dickman et al. [31]

Placebo for 1 week

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

3

4

13

15

0.19

0.79

0.43

0.54

0.89

1.03

46

43

46

Bautista et al. [32]

Lansoprazole 60 mg AM, 30 mg PM for 1 week SIS ≥50%

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

14

2

4

20

0.78

0.91

0.875

0.833

8.56

0.24

45

88

17

Bautista et al. [32]

Lansoprazole 60 mg AM, 30 mg PM for 1 week SIS ≥65%

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

15

1

3

21

0.83

0.95

0.93

0.88

18.33

0.17

45

94

13

Bautista et al. [32]

Placebo for 1 week

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

4

8

14

14

0.22

0.64

0.33

0.50

0.61

1.22

45

33

50

Fass et al. [33]

Omeprazole 40 mg AM, 20 mg PM for 1 week SIS ≥50%

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

18

2

5

12

0.78

0.86

0.90

0.71

5.48

0.25

62

90

29

Fass et al. [33]

Placebo for 1 week

Endoscopy (Hentzel-Dent grades) and/or 24 h pH-metry (>4.2% pH <4)

5

1

18

13

0.22

0.93

0.83

0.42

3.04

0.84

62

83

58

Pandak et al. [34]

Omeprazole 40 mg twice a day for 2 weeks SIS ≥50%

Endoscopy and/or 24 h pH-metry (>4.2% pH <4)

18

6

2

12

0.90

0.67

0.75

0.86

2.70

0.15

53

75

14

Pandak et al. [34]

Placebo for 2 weeks SIS ≥50%

Endoscopy and/or 24 h pH-metry (>4.2% pH <4)

1

3

19

15

0.05

0.83

0.25

0.44

0.30

1.14

53

25

56

Kim et al. [35]

NCCP GERD-related (TP) vs NCCP non-GERD-related (TN): rabeprazole for 1 week SIS ≥50%

Endoscopy (LA classification) and/or 24 h pH-metry (>4.0 pH <4)

8

6

8

20

0.50

0.77

0.57

0.71

2.17

0.65

38

57

29

Kim et al. [35]

NCCP GERD-related (TP) vs NCCP non-GERD-related (TN): rabeprazole for 2 weeks SIS ≥50%

Endoscopy (LA classification) and/or 24 h pH-metry (>4.0 pH <4)

13

7

3

19

0.81

0.73

0.65

0.86

3.02

0.26

38

65

14

Xia et al. [36]

Lansoprazole 30 mg once a day for 4 weeks SIS ≥50%

24 h pH-metry (De Meester pH <4, 7.5 s)

11

8

1

16

0.92

0.67

0.58

0.94

2.75

0.13

33

58

6

Xia et al. [36]

Placebo for 4 weeks SIS ≥50%

24 h pH-metry (De Meester pH <4, 7.5 s)

4

7

8

13

0.33

0.65

0.36

0.62

0.95

1.03

38

36

38

Kushnir et al. [37]

High-degree response on PPI (not specified)

24 pH-metry (≥4%, pH <4)

40

18

12

28

0.77

0.61

0.69

0.70

1.97

0.38

53

69

30

Kushnir et al. [37]

High-degree response on PPI

Positive Ghillibert probability estimate (GPE)

21

37

5

35

0.81

0.49

0.36

0.88

1.57

0.40

27

36

12

Kushnir et al. [37]

High-degree response on PPI

Association of chest pain with pH <4 in reference standard: SI ≥50%

19

39

6

34

0.76

0.47

0.33

0.85

1.42

0.52

26

33

15

Kushnir et al. [37]

High-degree response on PPI

24 h pH-metry and positive GPE

15

43

2

38

0.88

0.47

0.26

0.95

1.66

0.25

17

26

5

Kushnir et al. [37]

High-degree response on PPI

24 h pH-metry and SI ≥50%

16

42

2

38

0.89

0.48

0.28

0.95

1.69

0.23

18

28

5

Kushnir et al. [37]

High-degree response on PPI

24 h pH-metry and SI ≥50% and positive GPE

14

44

1

39

0.93

0.47

0.24

0.98

1.76

0.14

15

24

2

Symptom index

Singh et al. [28]

Association of chest pain with pH <4 in reference standard: SI ≥50%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

19

38

15

81

0.56

0.68

0.33

0.84

1.75

0.65

22

33

16

Singh et al. [28]

Association of chest pain with pH <4 in reference standard: SI ≥25%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

23

59

11

60

0.68

0.50

0.28

0.85

1.36

0.64

22

28

15

Singh et al. [28]

Association of chest pain with pH <4 in reference standard: SI ≥75%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

8

5

26

114

0.24

0.96

0.62

0.81

5.60

0.80

22

62

19

Singh et al. [28]

Association of heartburn with pH <4 in reference standard: Symptom Index (SI) ≥50%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

40

32

3

78

0.93

0.71

0.56

0.96

3.20

0.10

28

56

4

Singh et al. [28]

Association of heartburn with pH <4 in reference standard: SI ≥25%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

41

40

2

70

0.95

0.64

0.51

0.97

2.62

0.07

28

51

3

Singh et al. [28]

Association of heartburn with pH <4 in reference standard: SI ≥75%

Endoscopy and/or 24 h pH-metry (De Meester >5.5% pH <4)

25

25

9

94

0.74

0.79

0.50

0.91

3.50

0.34

28

58

12

Ho et al. [29]

Association of chest pain with pH <4 in reference standard: SI >50%

24 h pH-metry (>4% pH <4, 4 s)

3

9

11

38

0.21

0.81

0.25

0.78

1.12

0.97

23

25

22

Lam et al. [30]

Association of chest pain with pH <4 in reference standard: SI ≥75%

24 h pH-metry (execution in acute stage)

13

0

15

13

0.46

1.00

1.00

0.48

13.03

0.54

68

97

54

Others

Lacima et al. [38]

24 h-manometry (pH <4)

Manometry during hospital stay

18

24

18

30

0.50

0.56

0.43

0.56

1.13

0.90

40

43

38

Provocation test

Cooke et al. [39]

NCCP during exertional pH-metry

24 h pH-metry (5.5% pH <4 for 10 s)

4

0

15

31

0.21

1.00

1.00

0.67

14.40

0.79

38

90

33

Cooke et al. [39]

Control group: CVD with angina: exertional pH-metry

24 h pH-metry (5.5% pH <4 for 10 s)

1

1

2

12

0.33

0.92

0.50

0.86

4.33

0.72

19

50

14

Bovero et al. [40]

NCCP with normal ECG during exertional pH-metry

24 h pH-metry (De Meester criteria: >4.5% pH <4))

17

1

29

20

0.37

0.95

0.94

0.41

7.76

0.66

69

94

59

Bovero et al. [40]

NCCP at rest: NCCP with normal ECG during exertional pH-metry

24 h pH-metry (De Meester criteria: >4.5% pH <4))

11

1

23

11

0.32

0.92

0.92

0.32

3.88

0.74

74

92

68

Bovero et al. [40]

NCCP exertion/mixed: NCCP with normal ECG during exertional pH-metry

24 h pH-metry (De Meester criteria: >4.5% pH <4))

6

0

6

9

0.50

1.00

1.00

0.60

10.00

0.50

57

93

40

Bovero et al. [40]

24 h pH-metry (De Meester criteria: >4.5% pH <4))

NCCP with normal ECG during exertional pH-metry

17

29

1

20

0.94

0.41

0.37

0.95

1.60

0.14

27

37

5

Bovero et al. [40]

24 h pH-metry (De Meester criteria: >4.5% pH <4))

NCCP at rest: NCCP with normal ECG during exertional pH-metry

11

23

1

11

0.92

0.32

0.32

0.92

1.36

0.26

26

32

8

Romand et al. [41]

NCCP: pH <4 for 10 s during exertional pH-metry

24 h pH-metry (De Meester criteria: >4.5% pH <4))

7

14

3

19

0.70

0.58

0.33

0.86

1.65

0.52

23

33

14

Abrahao et al. [42]

NCCP reproducible during balloon distension

Endoscopy (Savary-Miller) and/or manometry and/or pH-metry (De Meester criteria: >4.5% pH <4

14

1

21

4

0.40

0.80

0.93

0.16

2.00

0.75

88

93

84

Abrahao et al. [42]

NCCP reproducible during Tensilon test

Endoscopy (Savary-Miller) and/or manometry and/or pH-metry (De Meester criteria: >4.5% pH <4

6

2

29

3

0.17

0.60

0.75

0.09

0.43

1.38

88

75

91

Abrahao et al. [42]

NCCP reproducible during Bernstein test

Endoscopy (Savary-Miller) and/or manometry and/or pH-metry (De Meester criteria: >4.5% pH <4

9

1

26

4

0.26

0.80

0.90

0.13

1.29

0.93

88

90

87

Abrahao et al. [42]

Tensilon and Bernstein Test and balloon distension (+ if 1 test +)

Endoscopy (Savary-Miller) and/or manometry and/or pH-metry (De Meester criteria: >4.5% pH <4

20

3

15

2

0.57

0.40

0.87

0.12

0.95

1.07

88

87

88

Abrahao et al. [42]

NCCP reproducible during Tensilon test

Endoscopy (Savary-Miller) and/or pH-metry (De Meester criteria: >4.5% pH <4

6

2

26

6

0.19

0.75

0.75

0.19

0.75

1.08

80

75

81

Abrahao et al. [42]

NCCP reproducible during Bernstein test

Endoscopy (Savary-Miller) and/or pH-metry (De Meester criteria: >4.5% pH <4

8

2

24

6

0.25

0.75

0.80

0.20

1.00

1.00

80

80

80

Abrahao et al. [42]

NCCP reproducible during balloon distension

Endoscopy (Savary-Miller) and/or pH-metry (De Meester criteria: >4.5% pH <4

13

2

19

6

0.41

0.75

0.87

0.24

1.63

0.79

80

87

76

Abrahao et al. [42]

Tensilon and Bernstein Test and balloon distension (+ if 1 test +)

Endoscopy (Savary-Miller) and/or pH-metry (De Meester criteria: >4.5% pH <4

18

5

14

3

0.56

0.38

0.78

0.18

0.90

1.17

80

78

82

Ho et al. [29]

NCCP reproducible during Bernstein test

Endoscopy

4

7

3

56

0.57

0.89

0.36

0.95

5.14

0.48

10

36

5

Eosinophilia

Achem et al. [43]

Current GERD symptoms

Esophageal biopsies

10

26

14

121

0.42

0.82

0.28

0.90

2.36

0.71

14

28

10

Achem et al. [43]

Male gender or current GERD symptoms

Esophageal biopsies

18

69

6

78

0.75

0.53

0.21

0.93

1.60

0.47

14

21

7

Achem et al. [43]

Male gender or any abnormal EoE endoscopic finding

Esophageal biopsies

23

79

1

68

0.96

0.46

0.23

0.99

1.78

0.09

14

23

1

Achem et al. [43]

Current GERD symptoms or any abnormal EoE endoscopic finding

Esophageal biopsies

20

63

4

84

0.83

0.57

0.24

0.96

1.94

0.29

14

24

5

Musculoskeletal

Stochkendahl et al. [44]

Biomechanical dysfunction

Standardized examination protocol

112

120

0

70

1.00

0.37

0.48

1.00

1.58

0.00

37

48

0

Stochkendahl et al. [44]

≥3 of 5 overall palpation findings

Standardized examination protocol

111

124

1

66

0.99

0.35

0.47

0.99

1.52

0.03

37

47

1

Bosner et al. [45]

Chest wall symptom (CWS) score: localized muscle tension, stinging pain, pain reproducible by palpation, absence of cough, cut-off test negative 0 to 1 points

Interdisciplinary consensus: cardiologist, GP, research associate (based on reviewed baseline, follow-up data)

506

318

59

329

0.90

0.51

0.66

0.82

1.82

0.20

47

61

15

Bosner et al. [45]

CWS score: localized muscle tension, stinging pain, pain reproducible by palpation, absence of cough, cut-off test negative 0 to 2 points

Interdisciplinary consensus

357

135

208

512

0.63

0.79

0.76

0.67

3.02

0.47

47

72

29

Stochkendahl et al. [44]

Anterior chest wall tenderness

Standardized examination protocol

110

134

2

56

0.98

0.29

0.45

0.97

1.39

0.06

37

45

3

Stochkendahl et al. [44]

Angina pectoris (uncertain or negative)

Standardized examination protocol

109

147

3

43

0.97

0.23

0.43

0.94

1.26

0.12

37

43

7

Stochkendahl et al. [44]

Pain worse on movement of torso

Standardized examination protocol

32

16

80

174

0.29

0.92

0.67

0.69

3.39

0.78

37

67

32

Bosner et al. [45]

Pain worse with movement

Interdisciplinary consensus

221

119

344

528

0.39

0.82

0.65

0.61

2.13

0.75

47

65

40

Stochkendahl et al. [44]

Positive/possible belief in pain origin from muscle/joints

Standardized examination protocol

108

156

4

34

0.96

0.18

0.41

0.90

1.17

0.20

37

41

11

Stochkendahl et al. [44]

Pain relief on pain medication

Standardized examination protocol

25

13

87

177

0.22

0.93

0.66

0.67

3.26

0.83

37

66

33

Bosner et al. [45]

Pain reproducible by palpation

Interdisciplinary consensus

351

193

214

454

0.62

0.70

0.68

0.64

2.08

0.54

47

65

32

Stochkendahl et al. [44]

Paraspinal tenderness

Standardized examination protocol

90

112

22

78

0.80

0.41

0.45

0.78

1.36

0.48

37

45

22

Bosner et al. [45]

Localized muscle tension

Interdisciplinary consensus

346

164

219

483

0.61

0.75

0.71

0.66

2.41

0.52

47

68

32

Stochkendahl et al. [44]

Chest pain present now

Standardized examination protocol

92

116

20

74

0.82

0.39

0.44

0.79

1.35

0.46

37

44

21

Bosner et al. [45]

Pain now

Interdisciplinary consensus

328

327

237

320

0.58

0.49

0.50

0.57

1.15

0.85

47

50

43

Stochkendahl et al. [44]

Pain debut not during a meal

Standardized examination protocol

109

168

3

22

0.97

0.12

0.39

0.88

1.10

0.23

37

39

12

Stochkendahl et al. [44]

Sharp pain

Standardized examination protocol

39

35

73

155

0.35

0.82

0.53

0.68

1.89

0.80

37

53

32

Bosner et al. [45]

Stinging pain

Interdisciplinary consensus

299

184

266

463

0.53

0.72

0.62

0.63

1.87

0.66

47

62

37

Stochkendahl et al. [44]

Hard physical exercise at least once a week

Standardized examination protocol

42

60

70

130

0.38

0.68

0.41

0.65

1.19

0.91

37

41

35

Stochkendahl et al. [44]

Pain not provoked during a meal

Standardized examination protocol

109

170

3

20

0.97

0.11

0.39

0.87

1.09

0.25

37

39

13

Stochkendahl et al. [44]

Not sudden debut

Standardized examination protocol

53

31

59

159

0.47

0.84

0.63

0.73

2.90

0.63

37

63

27

Bosner et al. [45]

Pain >24 h

Interdisciplinary consensus

158

139

407

508

0.28

0.79

0.53

0.56

1.30

0.92

47

54

45

Stochkendahl et al. [44]

Age ≤49 years old

Standardized examination protocol

67

54

45

136

0.60

0.72

0.55

0.75

2.10

0.56

37

55

25

Bosner et al. [45]

Pain mostly at noon time

Interdisciplinary consensus

13

30

552

617

0.02

0.95

0.31

0.53

0.50

1.02

47

31

48

Bosner et al. [45]

Cough

Interdisciplinary consensus

31

129

534

518

0.06

0.80

0.19

0.49

0.28

1.18

47

20

51

Bosner et al. [45]

Known IHD

Interdisciplinary consensus

56

122

509

525

0.10

0.81

0.32

0.51

0.52

1.11

47

32

50

Bosner et al. [45]

Pain worse with breathing

Interdisciplinary consensus

138

123

427

524

0.24

0.81

0.53

0.55

1.28

0.93

47

53

45

Manchikanti et al. [46]

Chronic thoracic pain: lidocaine injection

Bupivacaine injection

22

14

_

_

0.61

_

Psychiatric

Kuijpers et al. [47]

Anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A score, cut-off ≥8)

Diagnosis Anxiety disorders (Mini International Neuropsychiatric Interview (gold standard))

195

71

3

75

0.98

0.51

0.73

0.96

2.03

0.03

58

73

4

Demiryoguran et al. [48]

Palpitation

Anxiety disorder: HADS-A score (cut-off ≥10)

18

25

31

80

0.37

0.76

0.42

0.72

1.54

0.83

31

41

27

Demiryoguran et al. [48]

Fear of dying

Anxiety disorder: HADS-A score (cut-off ≥10)

11

6

38

102

0.22

0.94

0.65

0.73

4.04

0.82

31

65

27

Demiryoguran et al. [48]

Light-headedness, dizziness, faintness

Anxiety disorder: HADS-A score (cut-off ≥10)

11

8

38

100

0.22

0.93

0.58

0.73

3.03

0.84

31

58

28

Demiryoguran et al. [48]

Chills or hot flushes

Anxiety disorder: HADS-A score (cut-off ≥10)

11

5

38

103

0.22

0.95

0.69

0.73

4.85

0.81

31

69

27

Demiryoguran et al. [48]

Shortness of breath

Anxiety disorder: HADS-A score (cut-off ≥10)

13

22

36

86

0.27

0.80

0.37

0.71

1.30

0.92

31

37

29

Demiryoguran et al. [48]

Nausea or gastric discomfort

Anxiety disorder: HADS-A score (cut-off ≥10)

9

10

40

98

0.18

0.91

0.47

0.71

1.98

0.90

31

47

29

Demiryoguran et al. [48]

Diaphoresis

Anxiety disorder: HADS-A score (cut-off ≥10)

19

12

30

96

0.39

0.89

0.61

0.76

3.49

0.69

31

61

24

Foldes-Busque et al. [49]

The Panic Screening Score (derivation population)

Panic disorder diagnosis (structured Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual of Mental Disorders, fourth edition DSM-IV (ADIS-IV))

53

19

31

98

0.63

0.84

0.74

0.76

3.89

0.44

42

74

24

Foldes-Busque et al. [49]

The Panic Screening Score (validation population)

Panic disorder diagnosis (structured ADIS-IV)

69

27

61

148

0.53

0.85

0.72

0.71

3.44

0.55

43

72

29

Katerndahl et al. [51]

GP diagnosis of panic disorder

Panic disorder (structured clinical Interview of Diagnostic and Statistical Manual of Mental Disorders, based on DSM-III-R)

2

2

26

21

0.07

0.91

0.50

0.45

0.82

1.02

55

50

55

Fleet et al. [50]

Panic disorder diagnosis: formula including Agoraphobia Cognitions QA, Mobility Inventory for Agoraphobia, Zone 12 Dermatome Pain Map, Sensory McGill Pain QA, Gender, Zone 25 (Validation population)

Panic Disorder (ADIS-R structured interview by psychologist)

32

41

17

122

0.65

0.75

0.44

0.88

2.60

0.46

23

44

12