Groups (n) | Bax | Bcl-2 | Bax/Bcl-2 |
---|
Sham (8) | 3.32 (0.92) | 2.74 (1.03) | 1.14 (0.22) |
Depression (8) | 9.47 (2.5)a
| 6.18 (2.21)a
| 1.55 (0.30)a
|
MI (13) | 27.63 (5.61)a, b
| 9.42 (3.75)a
| 2.83 (0.51)a, b
|
Post-MI depression (7) | 53.88 (16.18)a, b, c
| 14.82 (3.71)a, c
| 3.77 (0.64)a, b, c
|
- There was a significantly higher ratio of Bax:Bcl-2 (mean ± SEM) in the myocardium in the depression, MI (myocardial infarction) and post-MI depression groups than in the sham group (a P < 0.01). Furthermore, in the post-MI depression and MI groups there was a significantly higher ratio of Bax:Bcl-2 than in the depression group(b P < 0.01), and in the post-MI group there was a significantly higher ratio of Bax:Bcl-2 than in the MI group (c P < 0.01).