Figure 2

The association of fascin-1 with mortality in breast, colorectal, gastric, lung and esophageal carcinomas. The Forest plots show (A) Positive versus negative = positive fascin-1 staining versus negative fascin-1 staining; (B) High versus low = High fascin-1 staining versus low fascin-1 staining (see Methods for details of the scoring categorizations). In both A and B, squares indicate the study-specific effect estimate, with the size proportional to the inverse of the variance (I-V); horizontal lines show study-specific 95% confidence intervals. The diamonds are pooled estimates and their 95% confidence intervals, based on random or fixed effects meta-analysis models. The dashed vertical line is the overall pooled estimate across all included studies and carcinomas.