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Table 3 Smoking intensity (pack years) related to metabolites

From: Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study

Metabolites β estimate of pack year Δ (%) P
  (95% confidence interval)×10-3   
Men    
Arginine -1.1 (-3.6, 1.4) -0.11% 0.38
Aspartate 2.9 (-1.4, 7.1) 0.29% 0.20
Glutamate 2.9 (-1.2, 6.9) 0.29% 0.17
Ornithine -2.4 (-5.2, 0.3) -0.24% 0.09
Serine 1.1 (-1.3, 3.6) 0.11% 0.37
Kynurenine* -3.3 (-6.1, -0.5) -0.33% 0.02
PC aa C32:3 -1.4 (-4.3, 1.4) -0.14% 0.33
PC aa C34:1 -0.9 (-3.5, 1.6) -0.09% 0.48
PC aa C36:0 -2.3 (-4.9, 0.4) -0.23% 0.09
PC aa C36:1 -1.4 (-4.6, 1.8) -0.14% 0.39
PC aa C38:0 -2.1 (-4.9, 0.7) -0.21% 0.15
PC aa C38:3 1.2 (-1.7, 4.1) 0.12% 0.43
PC aa C40:4 1.3 (-2.5, 5.1) 0.13% 0.51
PC ae C34:3* -3.7 (-6.4, -0.9) -0.37% 0.01
PC ae C38:0* -3.6 (-6.6, -0.5) -0.36% 0.02
PC ae C38:6* -2.6 (-5.1, -0.1) -0.26% 0.04
PC ae C40:6 -1.7 (-4.4, 1.0) -0.17% 0.22
lysoPC a C18:2 -3.1 (-6.5, 0.3) -0.31% 0.07
Women    
Carnitine 1.1 (-4.3, 6.5) 0.11% 0.70
PC aa C32:1 0.2 (-10.5, 10.9) 0.02% 0.97
PC aa C36:1* 6.9 (0.6, 13.2) 0.69% 0.04
PC ae C34:3 -2.7 (-7.7, 2.2) -0.27% 0.54
SM (OH) C22:2 -2.8 (-7.7, 2.2) -0.28% 0.28
Glutamate 2.2 (-7.8, 12.2) 0.22% 0.67
  1. Results of linear regression of smoking intensity (pack years) on metabolite concentrations in men and women, adjusted for age, body mass index and alcohol consumption. All smoking-related metabolites presented in Table 2 are listed (*P <0.05). aa: diacyl-; ae: acyl-alkyl-; CS: current smokers; FS: former smokers; lysoPC: acyl-phosphatidylcholine; NS: never smokers; PC: phosphatidylcholine; SM (OH): hydroxysphingomyeline.