A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial

Table 3 Effects of the intervention on components of frailty by intention-to-treat analyses:

	Number	Intervention group (n = 120)	Control group (n = 121)	Percentage difference between groups or coefficient^a	P ^b
Frailty criteria
*Weight (kg)*
Change from 0 to 3 months	224	0.40 ±3.72	0.92 ±3.59	0.51 (-0.45 to 1.48)	0.29
Change from 0 to 12 months	210	0.72 ±5.98	1.48 ±5.09	0.78 (-0.72 to 2.28)	0.31
*Exhaustion*
Rate at 3 months (number (%))	225	47 (44%)	46 (39%)	4.2% (-8.7% to 17.1%)	0.52
Rate at 12 months (number (%))	213	29 (27%)	35 (33%)	-5.9% (-18.2% to 6.4%)	0.35
*Grip strength (kg)*
Change from 0 to 3 months	225	0.78 ±3.56	1.02 ±4.93	0.50 (-0.55 to 1.54)	0.35
Change from 0 to 12 months	213	0.93 ±4.62	1.88 ±5.75	1.18 (-0.13 to 2.49)	0.08
*Gait speed (meter/second)*
Change from 0 to 3 months	225	-0.006 ±0.155	-0.007 ±0.169	-0.004 (-0.046 to 0.039)	0.87
Change from 0 to 12 months	213	-0.049 ±0.183	0.019 ±0.230	0.068 (0.012 to 0.123)	0.02
*Low physical activity*
Rate at 3 months - No. (%)	225	59 (55%)	74 (63%)	-8.6% (-21.4% to 4.2%)	0.19
Rate at 12 months - No. (%)	213	67 (63%)	80 (76%)	-12.9% (-25.2% to -0.6%)	0.04

Data presented as mean, ±standard deviation, unless otherwise stated. ^aCoefficient from a linear regression model with follow-up values as a dependent variable and baseline values as a covariate. ^b P values, which were derived from linear regression models with baseline values as a covariate, are for the differences in mean between intervention and control group. Percentages are calculated based on number of participants available for follow-up.

ISSN: 1741-7015