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Table 3 Effects of the intervention on components of frailty by intention-to-treat analyses:

From: A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial

  Number Intervention group (n = 120) Control group (n = 121) Percentage difference between groups or coefficienta P b
Frailty criteria      
Weight (kg)      
Change from 0 to 3 months 224 0.40 ±3.72 0.92 ±3.59 0.51 (-0.45 to 1.48) 0.29
Change from 0 to 12 months 210 0.72 ±5.98 1.48 ±5.09 0.78 (-0.72 to 2.28) 0.31
Exhaustion      
Rate at 3 months (number (%)) 225 47 (44%) 46 (39%) 4.2% (-8.7% to 17.1%) 0.52
Rate at 12 months (number (%)) 213 29 (27%) 35 (33%) -5.9% (-18.2% to 6.4%) 0.35
Grip strength (kg)      
Change from 0 to 3 months 225 0.78 ±3.56 1.02 ±4.93 0.50 (-0.55 to 1.54) 0.35
Change from 0 to 12 months 213 0.93 ±4.62 1.88 ±5.75 1.18 (-0.13 to 2.49) 0.08
Gait speed (meter/second)      
Change from 0 to 3 months 225 -0.006 ±0.155 -0.007 ±0.169 -0.004 (-0.046 to 0.039) 0.87
Change from 0 to 12 months 213 -0.049 ±0.183 0.019 ±0.230 0.068 (0.012 to 0.123) 0.02
Low physical activity      
Rate at 3 months - No. (%) 225 59 (55%) 74 (63%) -8.6% (-21.4% to 4.2%) 0.19
Rate at 12 months - No. (%) 213 67 (63%) 80 (76%) -12.9% (-25.2% to -0.6%) 0.04
  1. Data presented as mean, ±standard deviation, unless otherwise stated. aCoefficient from a linear regression model with follow-up values as a dependent variable and baseline values as a covariate. b P values, which were derived from linear regression models with baseline values as a covariate, are for the differences in mean between intervention and control group. Percentages are calculated based on number of participants available for follow-up.