Forest plots depicting odds ratios for familial autoimmunity. The figure shows two different analyses. From top to bottom: (A) rheumatoid arthritis (RA), (B) multiple sclerosis (MS). Autoimmune diseases in first degree relatives through all the studies from a specific autoimmune disease present in the proband were analyzed. The summary effect (random effect model) is depicted as a diamond at the bottom of each analysis. The lateral points of each diamond indicate confidence intervals for this estimate. aNumbers represent different subgroups within the study.