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Figure 1 | BMC Medicine

Figure 1

From: 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus

Figure 1

16/6-Id injected mice displayed impaired performance in the novel object recognition test. Results are presented as the proportion of time spent near the old and new objects by the 16/6-Id (gray bars) and IgG control (black bars) injected mice. The control mice (IgG) significantly preferred the new object (64% vs. 36% for the proportion time near the new vs. old objects respectively; P = 0.01), while the 16/6-Id injected mice had no significant preference to either objects (56% vs. 44% new vs. old; P = 0.5). Results presented as mean ± SEM. * Statistically significant (P <0.05).

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