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Figure 2 | BMC Medicine

Figure 2

From: 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus

Figure 2

16/6-Id injected mice displayed impaired spatial memory in the Y-maze test. Results are presented as the proportion of time (mean ± SEM) spent in the new arm introduced by the 16/6-Id (gray bars) and IgG control (black bars) injected mice. In the figure it is shown that the control group (IgG injected) spent more time in the new lane as compared to the 16/6 injected group. They have recognized the old lane as known and preferred exploring the new lane, which means that their spatial memory is conserved. There was a significant difference in additional time spent in the new lane between the 16/6 and IgG group (0.46 vs. 0.09, P = 0.02 respectively). * Statistically significant (P <0.05).

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BMC Medicine

ISSN: 1741-7015

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